Item List

HTTP 200 OK
Allow: GET, HEAD, OPTIONS
Content-Type: application/json
Vary: Accept

{
    "count": 211645,
    "next": "https://rxproduct.petco.com/item/?format=api&limit=100&offset=197600",
    "previous": "https://rxproduct.petco.com/item/?format=api&limit=100&offset=197400",
    "results": [
        {
            "id": 197565,
            "pharmainfo": null
        },
        {
            "id": 197566,
            "pharmainfo": null
        },
        {
            "id": 197567,
            "pharmainfo": null
        },
        {
            "id": 197568,
            "pharmainfo": null
        },
        {
            "id": 197569,
            "pharmainfo": null
        },
        {
            "id": 197570,
            "pharmainfo": null
        },
        {
            "id": 197571,
            "pharmainfo": null
        },
        {
            "id": 197572,
            "pharmainfo": null
        },
        {
            "id": 197573,
            "pharmainfo": null
        },
        {
            "id": 197574,
            "pharmainfo": null
        },
        {
            "id": 197575,
            "pharmainfo": null
        },
        {
            "id": 197576,
            "pharmainfo": {
                "html": "<div><b>Product details</b></div><div>Credelio (lotilaner) for Dogs is a beef-flavored, chewable tablet administered once per month to kill adult fleas, treat and prevent flea infestations, and treat and control tick infestations (lone star tick, American dog tick, black-legged tick, and brown dog tick) in dogs and puppies 8 weeks of age and older, and weighing 4.4 pounds or greater.</div><ul><li>Tick and flea treatment &amp; infestation prevention for dogs 8 weeks of age and older, and weighing 4.4 pounds or greater</li><li>Fast-acting ingredients start killing <i>Ixodes ricinus</i> ticks &amp; adult fleas in just 4 hours</li><li>Kills 100% of fleas in 12 hours &amp; stays effective for 30 days</li><li>Easy to give your dog; no greasy, messy application</li><li>Small, beef-flavored chewable tablet accepted by 100% of dogs tested (Karadzovska D, Chappell K, Coble S, et al. A randomized, controlled field study to assess the efficacy and safety of lotilaner flavored chewable tablets (Credelio&trade;) in eliminating fleas in client-owned dogs in the USA. Parasite Vector. 2017;10(1):528.)</li></ul><div><br></div><div><b>Product sourced directly from the manufacturer or their approved distributor. Guaranteed genuine product backed by the manufacturer.</b></div><div><br><hr></div><div><br></div><div><b>For</b></div><div>Dogs (8 weeks of age and older)</div><div><br></div><div><b>Active ingredient(s)</b></div><div>Lotilaner</div><div><br></div><div><b>Inactive ingredients</b></div><div>Complete inactive ingredients list not provided by manufacturer.</div><div><br></div><div><b>Brand name</b></div><div>Credelio for Dogs</div><div><br></div><div><b>Drug class</b></div><div>Isoxazoline ectoparasiticide</div><div><br></div><div><b>Product flavoring</b></div><div>Credelio for Dogs is “beef” flavored.</div><div><i>*Contains pork liver, soy, barley, wheat, lactose (does not contain actual beef)</i></div><div><br></div><div><b>Manufacturer</b></div><div>Elanco</div><div><br></div><div><b>Product strength &amp; size</b></div><div><style>    table, th, td {        border: 1px solid;        border-collapse: collapse;        padding: 8px;        text-align: center;    }</style><table style=\"width: max(75%, min(319px, 100%))\"><tbody><tr><th><b>Weight range</b></th><th><b>Lotilaner (per chewable tablet)</b></th><th><b>Chewable tablets administered</b></th></tr><tr><td>4.4 to 6 lbs</td><td>56.25 mg</td><td>One</td></tr><tr><td>6.1 to 12 lbs</td><td>112.5 mg</td><td>One</td></tr><tr><td>12.1 to 25 lbs</td><td>225 mg</td><td>One</td></tr><tr><td>25.1 to 50 lbs</td><td>450 mg</td><td>One</td></tr><tr><td>50.1 to 100* lbs</td><td>900 mg</td><td>One</td></tr></tbody></table></div><div><br></div><div>*For dogs over 100 lbs, administer the appropriate combination of chewable tablets to cover your pet&rsquo;s body weight.</div><div><br><hr></div><div><br></div><div><b>Usage</b></div><div><i>*For complete product information, please review the full prescribing information in the manufacturer package insert.</i></div><div><br></div><div>Manufacturer Dosage and Administration:</div><div>Credelio is given orally once a month, at the minimum dosage of 9 mg/lb (20 mg/kg).</div><div>Credelio must be administered with food or given within 30 minutes of feeding.</div><div>Treatment with Credelio can begin at any time of the year and can continue year-round without interruption.</div><div><br></div><div><b>Missed doses</b></div><div>If a dose is missed, administer Credelio with food and resume a monthly dosing schedule to minimize the opportunity for tick and flea re-infestations. Consult your veterinarian about any concerns you may have about ticks and fleas due to the late/missed dose.</div><div><br></div><div><b>Storage</b></div><div>Store in a cool, dry place at a controlled room temperature (59 to 77&deg;F, excursions permitted between 41 to 104&deg;F). Keep out of the reach of children and pets. Tablets should remain sealed in their original packaging and should only be taken out of the blister pack at the time of dosing. Store away from heat and direct sunlight.</div><div>Do not store in the bathroom, near the kitchen sink, or in damp places. The medicine may break down if exposed to heat or moisture.</div><div><br></div><div><hr></div><div><br></div><div><b>Side effects</b></div><div>Credelio is generally well tolerated, and side effects are considered uncommon when given at the recommended dosage. The most common side effects of this medication are vomiting, diarrhea, decreased appetite, weight loss, elevated blood urea nitrogen (BUN), and increased urination.</div><div><br></div><div>Contact your veterinarian immediately if your pet experiences persistent vomiting, complete loss of appetite, or if you notice your pet has a seizure, tremors, extreme weakness, or decreased coordination (e.g., stumbling, difficulty walking).</div><div><br></div><div>Notify your veterinarian if your pet experiences any of the effects described above, or if you notice any other side effects that are persistent or troublesome.</div><div>If you notice anything unusual, please consult your veterinarian.</div><div><br></div><div><b>Precautions</b></div><div><i>*For complete product information including warnings and precautions, please refer to the manufacturer package insert.</i></div><div><br></div><div>For oral use in dogs only- not for human use. Keep this and all drugs out of the reach of children. Keep Credelio in a secure location out of reach of dogs, cats, and other animals to prevent accidental ingestion or overdose.</div><div><br></div><div>Lotilaner is a member of the isoxazoline class. This class has been associated with neurologic adverse reactions including tremors, ataxia, and seizures. Seizures have been reported in dogs receiving isoxazoline class drugs, even in dogs without a history of seizures. Use with caution in dogs with a history of seizures or neurologic disorders.</div><div>The safe use of Credelio in breeding, pregnant, or lactating dogs has not been evaluated. Discuss the risks of using this medication with your veterinarian if your pet is in one of these groups.</div><div><br></div><div>Do not administer to animals with a known history or suspected allergy/hypersensitivity to any isoxazoline class drug, including this medication or any of its ingredients. Allergic reactions to medications may occur. Be sure to inform Vetsource and your veterinarian if your pet has any known drug sensitivities or allergies.</div><div>If your pet displays symptoms of an allergic reaction, discontinue therapy and call your veterinarian immediately or seek emergency veterinary attention. Symptoms may include (but are not limited to): swollen lips, tongue, face, or airways; difficulty breathing; agitation; profuse salivation; and widespread hives or itching.</div><div><br></div><div><b>Drug and food interactions</b></div><div>There are no documented drug or food interactions with Credelio for Dogs.</div><div>Contact your veterinarian if your pet experiences any unusual reactions when different medications are given together.</div><div><br></div><div>Please ensure your veterinarian is aware of all medications and supplements that your pet is currently receiving. Your veterinarian may prescribe multiple medications, even if a potential drug interaction may occur. In these instances, your veterinarian may adjust the dosages or monitor your pet more closely.</div><div><br></div><div><b>Adverse reactions</b></div><div>If you are concerned that your pet has experienced an adverse reaction to this medication, please contact the manufacturer Elanco US at 1-888-545-5973 or Vetsource Pet Owner Care at 877-738-4443.</div><div><br></div><div><b>Overdose</b></div><div>If you have any reason to suspect an overdose, call your doctor/veterinarian or the appropriate poison control resource immediately.</div><div><br></div><div>For humans:</div><div>The national toll-free Poison Help line, 1-800-222-1222, will connect you to your local poison center in case of emergency. This service is available nationwide and in most U.S. territories.</div><div><br></div><div>For animals:</div><div>The ASPCA Animal Poison Control Center is available 24 hours a day, 365 days a year at 888-426-4435.</div><div>Pet Poison Helpline&reg; also provides a 24/7 animal poison control service at 855-764-7661.</div><div><br></div><div><i>*Please note: this information is for third-party services and is provided for convenience in case of potential poison-related emergencies. There may be consultation fee for these services.</i></div><div><br></div><div><b>Disclaimer</b></div><div><b>The content provided on this page is NOT medical advice.</b></div><div>All content, including the images and product description above, is intended for general informational purposes only and should not be considered a substitute for professional veterinary consultation, diagnosis, or treatment.</div><div>Consult your veterinarian for complete information about this product and how it fits into your pet's individual treatment plan.</div><div><br><hr></div><div><i>Last revised: 8/19/2025</i></div>"
            }
        },
        {
            "id": 197577,
            "pharmainfo": {
                "html": "<div><b>Product details</b></div><div>Credelio (lotilaner) for Dogs is a beef-flavored, chewable tablet administered once per month to kill adult fleas, treat and prevent flea infestations, and treat and control tick infestations (lone star tick, American dog tick, black-legged tick, and brown dog tick) in dogs and puppies 8 weeks of age and older, and weighing 4.4 pounds or greater.</div><ul><li>Tick and flea treatment &amp; infestation prevention for dogs 8 weeks of age and older, and weighing 4.4 pounds or greater</li><li>Fast-acting ingredients start killing <i>Ixodes ricinus</i> ticks &amp; adult fleas in just 4 hours</li><li>Kills 100% of fleas in 12 hours &amp; stays effective for 30 days</li><li>Easy to give your dog; no greasy, messy application</li><li>Small, beef-flavored chewable tablet accepted by 100% of dogs tested (Karadzovska D, Chappell K, Coble S, et al. A randomized, controlled field study to assess the efficacy and safety of lotilaner flavored chewable tablets (Credelio&trade;) in eliminating fleas in client-owned dogs in the USA. Parasite Vector. 2017;10(1):528.)</li></ul><div><br></div><div><b>Product sourced directly from the manufacturer or their approved distributor. Guaranteed genuine product backed by the manufacturer.</b></div><div><br><hr></div><div><br></div><div><b>For</b></div><div>Dogs (8 weeks of age and older)</div><div><br></div><div><b>Active ingredient(s)</b></div><div>Lotilaner</div><div><br></div><div><b>Inactive ingredients</b></div><div>Complete inactive ingredients list not provided by manufacturer.</div><div><br></div><div><b>Brand name</b></div><div>Credelio for Dogs</div><div><br></div><div><b>Drug class</b></div><div>Isoxazoline ectoparasiticide</div><div><br></div><div><b>Product flavoring</b></div><div>Credelio for Dogs is “beef” flavored.</div><div><i>*Contains pork liver, soy, barley, wheat, lactose (does not contain actual beef)</i></div><div><br></div><div><b>Manufacturer</b></div><div>Elanco</div><div><br></div><div><b>Product strength &amp; size</b></div><div><style>    table, th, td {        border: 1px solid;        border-collapse: collapse;        padding: 8px;        text-align: center;    }</style><table style=\"width: max(75%, min(319px, 100%))\"><tbody><tr><th><b>Weight range</b></th><th><b>Lotilaner (per chewable tablet)</b></th><th><b>Chewable tablets administered</b></th></tr><tr><td>4.4 to 6 lbs</td><td>56.25 mg</td><td>One</td></tr><tr><td>6.1 to 12 lbs</td><td>112.5 mg</td><td>One</td></tr><tr><td>12.1 to 25 lbs</td><td>225 mg</td><td>One</td></tr><tr><td>25.1 to 50 lbs</td><td>450 mg</td><td>One</td></tr><tr><td>50.1 to 100* lbs</td><td>900 mg</td><td>One</td></tr></tbody></table></div><div><br></div><div>*For dogs over 100 lbs, administer the appropriate combination of chewable tablets to cover your pet&rsquo;s body weight.</div><div><br><hr></div><div><br></div><div><b>Usage</b></div><div><i>*For complete product information, please review the full prescribing information in the manufacturer package insert.</i></div><div><br></div><div>Manufacturer Dosage and Administration:</div><div>Credelio is given orally once a month, at the minimum dosage of 9 mg/lb (20 mg/kg).</div><div>Credelio must be administered with food or given within 30 minutes of feeding.</div><div>Treatment with Credelio can begin at any time of the year and can continue year-round without interruption.</div><div><br></div><div><b>Missed doses</b></div><div>If a dose is missed, administer Credelio with food and resume a monthly dosing schedule to minimize the opportunity for tick and flea re-infestations. Consult your veterinarian about any concerns you may have about ticks and fleas due to the late/missed dose.</div><div><br></div><div><b>Storage</b></div><div>Store in a cool, dry place at a controlled room temperature (59 to 77&deg;F, excursions permitted between 41 to 104&deg;F). Keep out of the reach of children and pets. Tablets should remain sealed in their original packaging and should only be taken out of the blister pack at the time of dosing. Store away from heat and direct sunlight.</div><div>Do not store in the bathroom, near the kitchen sink, or in damp places. The medicine may break down if exposed to heat or moisture.</div><div><br></div><div><hr></div><div><br></div><div><b>Side effects</b></div><div>Credelio is generally well tolerated, and side effects are considered uncommon when given at the recommended dosage. The most common side effects of this medication are vomiting, diarrhea, decreased appetite, weight loss, elevated blood urea nitrogen (BUN), and increased urination.</div><div><br></div><div>Contact your veterinarian immediately if your pet experiences persistent vomiting, complete loss of appetite, or if you notice your pet has a seizure, tremors, extreme weakness, or decreased coordination (e.g., stumbling, difficulty walking).</div><div><br></div><div>Notify your veterinarian if your pet experiences any of the effects described above, or if you notice any other side effects that are persistent or troublesome.</div><div>If you notice anything unusual, please consult your veterinarian.</div><div><br></div><div><b>Precautions</b></div><div><i>*For complete product information including warnings and precautions, please refer to the manufacturer package insert.</i></div><div><br></div><div>For oral use in dogs only- not for human use. Keep this and all drugs out of the reach of children. Keep Credelio in a secure location out of reach of dogs, cats, and other animals to prevent accidental ingestion or overdose.</div><div><br></div><div>Lotilaner is a member of the isoxazoline class. This class has been associated with neurologic adverse reactions including tremors, ataxia, and seizures. Seizures have been reported in dogs receiving isoxazoline class drugs, even in dogs without a history of seizures. Use with caution in dogs with a history of seizures or neurologic disorders.</div><div>The safe use of Credelio in breeding, pregnant, or lactating dogs has not been evaluated. Discuss the risks of using this medication with your veterinarian if your pet is in one of these groups.</div><div><br></div><div>Do not administer to animals with a known history or suspected allergy/hypersensitivity to any isoxazoline class drug, including this medication or any of its ingredients. Allergic reactions to medications may occur. Be sure to inform Vetsource and your veterinarian if your pet has any known drug sensitivities or allergies.</div><div>If your pet displays symptoms of an allergic reaction, discontinue therapy and call your veterinarian immediately or seek emergency veterinary attention. Symptoms may include (but are not limited to): swollen lips, tongue, face, or airways; difficulty breathing; agitation; profuse salivation; and widespread hives or itching.</div><div><br></div><div><b>Drug and food interactions</b></div><div>There are no documented drug or food interactions with Credelio for Dogs.</div><div>Contact your veterinarian if your pet experiences any unusual reactions when different medications are given together.</div><div><br></div><div>Please ensure your veterinarian is aware of all medications and supplements that your pet is currently receiving. Your veterinarian may prescribe multiple medications, even if a potential drug interaction may occur. In these instances, your veterinarian may adjust the dosages or monitor your pet more closely.</div><div><br></div><div><b>Adverse reactions</b></div><div>If you are concerned that your pet has experienced an adverse reaction to this medication, please contact the manufacturer Elanco US at 1-888-545-5973 or Vetsource Pet Owner Care at 877-738-4443.</div><div><br></div><div><b>Overdose</b></div><div>If you have any reason to suspect an overdose, call your doctor/veterinarian or the appropriate poison control resource immediately.</div><div><br></div><div>For humans:</div><div>The national toll-free Poison Help line, 1-800-222-1222, will connect you to your local poison center in case of emergency. This service is available nationwide and in most U.S. territories.</div><div><br></div><div>For animals:</div><div>The ASPCA Animal Poison Control Center is available 24 hours a day, 365 days a year at 888-426-4435.</div><div>Pet Poison Helpline&reg; also provides a 24/7 animal poison control service at 855-764-7661.</div><div><br></div><div><i>*Please note: this information is for third-party services and is provided for convenience in case of potential poison-related emergencies. There may be consultation fee for these services.</i></div><div><br></div><div><b>Disclaimer</b></div><div><b>The content provided on this page is NOT medical advice.</b></div><div>All content, including the images and product description above, is intended for general informational purposes only and should not be considered a substitute for professional veterinary consultation, diagnosis, or treatment.</div><div>Consult your veterinarian for complete information about this product and how it fits into your pet's individual treatment plan.</div><div><br><hr></div><div><i>Last revised: 8/19/2025</i></div>"
            }
        },
        {
            "id": 197578,
            "pharmainfo": {
                "html": "<div><b>Product details</b></div><div>Credelio (lotilaner) for Dogs is a beef-flavored, chewable tablet administered once per month to kill adult fleas, treat and prevent flea infestations, and treat and control tick infestations (lone star tick, American dog tick, black-legged tick, and brown dog tick) in dogs and puppies 8 weeks of age and older, and weighing 4.4 pounds or greater.</div><ul><li>Tick and flea treatment &amp; infestation prevention for dogs 8 weeks of age and older, and weighing 4.4 pounds or greater</li><li>Fast-acting ingredients start killing <i>Ixodes ricinus</i> ticks &amp; adult fleas in just 4 hours</li><li>Kills 100% of fleas in 12 hours &amp; stays effective for 30 days</li><li>Easy to give your dog; no greasy, messy application</li><li>Small, beef-flavored chewable tablet accepted by 100% of dogs tested (Karadzovska D, Chappell K, Coble S, et al. A randomized, controlled field study to assess the efficacy and safety of lotilaner flavored chewable tablets (Credelio&trade;) in eliminating fleas in client-owned dogs in the USA. Parasite Vector. 2017;10(1):528.)</li></ul><div><br></div><div><b>Product sourced directly from the manufacturer or their approved distributor. Guaranteed genuine product backed by the manufacturer.</b></div><div><br><hr></div><div><br></div><div><b>For</b></div><div>Dogs (8 weeks of age and older)</div><div><br></div><div><b>Active ingredient(s)</b></div><div>Lotilaner</div><div><br></div><div><b>Inactive ingredients</b></div><div>Complete inactive ingredients list not provided by manufacturer.</div><div><br></div><div><b>Brand name</b></div><div>Credelio for Dogs</div><div><br></div><div><b>Drug class</b></div><div>Isoxazoline ectoparasiticide</div><div><br></div><div><b>Product flavoring</b></div><div>Credelio for Dogs is “beef” flavored.</div><div><i>*Contains pork liver, soy, barley, wheat, lactose (does not contain actual beef)</i></div><div><br></div><div><b>Manufacturer</b></div><div>Elanco</div><div><br></div><div><b>Product strength &amp; size</b></div><div><style>    table, th, td {        border: 1px solid;        border-collapse: collapse;        padding: 8px;        text-align: center;    }</style><table style=\"width: max(75%, min(319px, 100%))\"><tbody><tr><th><b>Weight range</b></th><th><b>Lotilaner (per chewable tablet)</b></th><th><b>Chewable tablets administered</b></th></tr><tr><td>4.4 to 6 lbs</td><td>56.25 mg</td><td>One</td></tr><tr><td>6.1 to 12 lbs</td><td>112.5 mg</td><td>One</td></tr><tr><td>12.1 to 25 lbs</td><td>225 mg</td><td>One</td></tr><tr><td>25.1 to 50 lbs</td><td>450 mg</td><td>One</td></tr><tr><td>50.1 to 100* lbs</td><td>900 mg</td><td>One</td></tr></tbody></table></div><div><br></div><div>*For dogs over 100 lbs, administer the appropriate combination of chewable tablets to cover your pet&rsquo;s body weight.</div><div><br><hr></div><div><br></div><div><b>Usage</b></div><div><i>*For complete product information, please review the full prescribing information in the manufacturer package insert.</i></div><div><br></div><div>Manufacturer Dosage and Administration:</div><div>Credelio is given orally once a month, at the minimum dosage of 9 mg/lb (20 mg/kg).</div><div>Credelio must be administered with food or given within 30 minutes of feeding.</div><div>Treatment with Credelio can begin at any time of the year and can continue year-round without interruption.</div><div><br></div><div><b>Missed doses</b></div><div>If a dose is missed, administer Credelio with food and resume a monthly dosing schedule to minimize the opportunity for tick and flea re-infestations. Consult your veterinarian about any concerns you may have about ticks and fleas due to the late/missed dose.</div><div><br></div><div><b>Storage</b></div><div>Store in a cool, dry place at a controlled room temperature (59 to 77&deg;F, excursions permitted between 41 to 104&deg;F). Keep out of the reach of children and pets. Tablets should remain sealed in their original packaging and should only be taken out of the blister pack at the time of dosing. Store away from heat and direct sunlight.</div><div>Do not store in the bathroom, near the kitchen sink, or in damp places. The medicine may break down if exposed to heat or moisture.</div><div><br></div><div><hr></div><div><br></div><div><b>Side effects</b></div><div>Credelio is generally well tolerated, and side effects are considered uncommon when given at the recommended dosage. The most common side effects of this medication are vomiting, diarrhea, decreased appetite, weight loss, elevated blood urea nitrogen (BUN), and increased urination.</div><div><br></div><div>Contact your veterinarian immediately if your pet experiences persistent vomiting, complete loss of appetite, or if you notice your pet has a seizure, tremors, extreme weakness, or decreased coordination (e.g., stumbling, difficulty walking).</div><div><br></div><div>Notify your veterinarian if your pet experiences any of the effects described above, or if you notice any other side effects that are persistent or troublesome.</div><div>If you notice anything unusual, please consult your veterinarian.</div><div><br></div><div><b>Precautions</b></div><div><i>*For complete product information including warnings and precautions, please refer to the manufacturer package insert.</i></div><div><br></div><div>For oral use in dogs only- not for human use. Keep this and all drugs out of the reach of children. Keep Credelio in a secure location out of reach of dogs, cats, and other animals to prevent accidental ingestion or overdose.</div><div><br></div><div>Lotilaner is a member of the isoxazoline class. This class has been associated with neurologic adverse reactions including tremors, ataxia, and seizures. Seizures have been reported in dogs receiving isoxazoline class drugs, even in dogs without a history of seizures. Use with caution in dogs with a history of seizures or neurologic disorders.</div><div>The safe use of Credelio in breeding, pregnant, or lactating dogs has not been evaluated. Discuss the risks of using this medication with your veterinarian if your pet is in one of these groups.</div><div><br></div><div>Do not administer to animals with a known history or suspected allergy/hypersensitivity to any isoxazoline class drug, including this medication or any of its ingredients. Allergic reactions to medications may occur. Be sure to inform Vetsource and your veterinarian if your pet has any known drug sensitivities or allergies.</div><div>If your pet displays symptoms of an allergic reaction, discontinue therapy and call your veterinarian immediately or seek emergency veterinary attention. Symptoms may include (but are not limited to): swollen lips, tongue, face, or airways; difficulty breathing; agitation; profuse salivation; and widespread hives or itching.</div><div><br></div><div><b>Drug and food interactions</b></div><div>There are no documented drug or food interactions with Credelio for Dogs.</div><div>Contact your veterinarian if your pet experiences any unusual reactions when different medications are given together.</div><div><br></div><div>Please ensure your veterinarian is aware of all medications and supplements that your pet is currently receiving. Your veterinarian may prescribe multiple medications, even if a potential drug interaction may occur. In these instances, your veterinarian may adjust the dosages or monitor your pet more closely.</div><div><br></div><div><b>Adverse reactions</b></div><div>If you are concerned that your pet has experienced an adverse reaction to this medication, please contact the manufacturer Elanco US at 1-888-545-5973 or Vetsource Pet Owner Care at 877-738-4443.</div><div><br></div><div><b>Overdose</b></div><div>If you have any reason to suspect an overdose, call your doctor/veterinarian or the appropriate poison control resource immediately.</div><div><br></div><div>For humans:</div><div>The national toll-free Poison Help line, 1-800-222-1222, will connect you to your local poison center in case of emergency. This service is available nationwide and in most U.S. territories.</div><div><br></div><div>For animals:</div><div>The ASPCA Animal Poison Control Center is available 24 hours a day, 365 days a year at 888-426-4435.</div><div>Pet Poison Helpline&reg; also provides a 24/7 animal poison control service at 855-764-7661.</div><div><br></div><div><i>*Please note: this information is for third-party services and is provided for convenience in case of potential poison-related emergencies. There may be consultation fee for these services.</i></div><div><br></div><div><b>Disclaimer</b></div><div><b>The content provided on this page is NOT medical advice.</b></div><div>All content, including the images and product description above, is intended for general informational purposes only and should not be considered a substitute for professional veterinary consultation, diagnosis, or treatment.</div><div>Consult your veterinarian for complete information about this product and how it fits into your pet's individual treatment plan.</div><div><br><hr></div><div><i>Last revised: 8/19/2025</i></div>"
            }
        },
        {
            "id": 197579,
            "pharmainfo": {
                "html": "<div><b>Product details</b></div><div>Credelio (lotilaner) for Dogs is a beef-flavored, chewable tablet administered once per month to kill adult fleas, treat and prevent flea infestations, and treat and control tick infestations (lone star tick, American dog tick, black-legged tick, and brown dog tick) in dogs and puppies 8 weeks of age and older, and weighing 4.4 pounds or greater.</div><ul><li>Tick and flea treatment &amp; infestation prevention for dogs 8 weeks of age and older, and weighing 4.4 pounds or greater</li><li>Fast-acting ingredients start killing <i>Ixodes ricinus</i> ticks &amp; adult fleas in just 4 hours</li><li>Kills 100% of fleas in 12 hours &amp; stays effective for 30 days</li><li>Easy to give your dog; no greasy, messy application</li><li>Small, beef-flavored chewable tablet accepted by 100% of dogs tested (Karadzovska D, Chappell K, Coble S, et al. A randomized, controlled field study to assess the efficacy and safety of lotilaner flavored chewable tablets (Credelio&trade;) in eliminating fleas in client-owned dogs in the USA. Parasite Vector. 2017;10(1):528.)</li></ul><div><br></div><div><b>Product sourced directly from the manufacturer or their approved distributor. Guaranteed genuine product backed by the manufacturer.</b></div><div><br><hr></div><div><br></div><div><b>For</b></div><div>Dogs (8 weeks of age and older)</div><div><br></div><div><b>Active ingredient(s)</b></div><div>Lotilaner</div><div><br></div><div><b>Inactive ingredients</b></div><div>Complete inactive ingredients list not provided by manufacturer.</div><div><br></div><div><b>Brand name</b></div><div>Credelio for Dogs</div><div><br></div><div><b>Drug class</b></div><div>Isoxazoline ectoparasiticide</div><div><br></div><div><b>Product flavoring</b></div><div>Credelio for Dogs is “beef” flavored.</div><div><i>*Contains pork liver, soy, barley, wheat, lactose (does not contain actual beef)</i></div><div><br></div><div><b>Manufacturer</b></div><div>Elanco</div><div><br></div><div><b>Product strength &amp; size</b></div><div><style>    table, th, td {        border: 1px solid;        border-collapse: collapse;        padding: 8px;        text-align: center;    }</style><table style=\"width: max(75%, min(319px, 100%))\"><tbody><tr><th><b>Weight range</b></th><th><b>Lotilaner (per chewable tablet)</b></th><th><b>Chewable tablets administered</b></th></tr><tr><td>4.4 to 6 lbs</td><td>56.25 mg</td><td>One</td></tr><tr><td>6.1 to 12 lbs</td><td>112.5 mg</td><td>One</td></tr><tr><td>12.1 to 25 lbs</td><td>225 mg</td><td>One</td></tr><tr><td>25.1 to 50 lbs</td><td>450 mg</td><td>One</td></tr><tr><td>50.1 to 100* lbs</td><td>900 mg</td><td>One</td></tr></tbody></table></div><div><br></div><div>*For dogs over 100 lbs, administer the appropriate combination of chewable tablets to cover your pet&rsquo;s body weight.</div><div><br><hr></div><div><br></div><div><b>Usage</b></div><div><i>*For complete product information, please review the full prescribing information in the manufacturer package insert.</i></div><div><br></div><div>Manufacturer Dosage and Administration:</div><div>Credelio is given orally once a month, at the minimum dosage of 9 mg/lb (20 mg/kg).</div><div>Credelio must be administered with food or given within 30 minutes of feeding.</div><div>Treatment with Credelio can begin at any time of the year and can continue year-round without interruption.</div><div><br></div><div><b>Missed doses</b></div><div>If a dose is missed, administer Credelio with food and resume a monthly dosing schedule to minimize the opportunity for tick and flea re-infestations. Consult your veterinarian about any concerns you may have about ticks and fleas due to the late/missed dose.</div><div><br></div><div><b>Storage</b></div><div>Store in a cool, dry place at a controlled room temperature (59 to 77&deg;F, excursions permitted between 41 to 104&deg;F). Keep out of the reach of children and pets. Tablets should remain sealed in their original packaging and should only be taken out of the blister pack at the time of dosing. Store away from heat and direct sunlight.</div><div>Do not store in the bathroom, near the kitchen sink, or in damp places. The medicine may break down if exposed to heat or moisture.</div><div><br></div><div><hr></div><div><br></div><div><b>Side effects</b></div><div>Credelio is generally well tolerated, and side effects are considered uncommon when given at the recommended dosage. The most common side effects of this medication are vomiting, diarrhea, decreased appetite, weight loss, elevated blood urea nitrogen (BUN), and increased urination.</div><div><br></div><div>Contact your veterinarian immediately if your pet experiences persistent vomiting, complete loss of appetite, or if you notice your pet has a seizure, tremors, extreme weakness, or decreased coordination (e.g., stumbling, difficulty walking).</div><div><br></div><div>Notify your veterinarian if your pet experiences any of the effects described above, or if you notice any other side effects that are persistent or troublesome.</div><div>If you notice anything unusual, please consult your veterinarian.</div><div><br></div><div><b>Precautions</b></div><div><i>*For complete product information including warnings and precautions, please refer to the manufacturer package insert.</i></div><div><br></div><div>For oral use in dogs only- not for human use. Keep this and all drugs out of the reach of children. Keep Credelio in a secure location out of reach of dogs, cats, and other animals to prevent accidental ingestion or overdose.</div><div><br></div><div>Lotilaner is a member of the isoxazoline class. This class has been associated with neurologic adverse reactions including tremors, ataxia, and seizures. Seizures have been reported in dogs receiving isoxazoline class drugs, even in dogs without a history of seizures. Use with caution in dogs with a history of seizures or neurologic disorders.</div><div>The safe use of Credelio in breeding, pregnant, or lactating dogs has not been evaluated. Discuss the risks of using this medication with your veterinarian if your pet is in one of these groups.</div><div><br></div><div>Do not administer to animals with a known history or suspected allergy/hypersensitivity to any isoxazoline class drug, including this medication or any of its ingredients. Allergic reactions to medications may occur. Be sure to inform Vetsource and your veterinarian if your pet has any known drug sensitivities or allergies.</div><div>If your pet displays symptoms of an allergic reaction, discontinue therapy and call your veterinarian immediately or seek emergency veterinary attention. Symptoms may include (but are not limited to): swollen lips, tongue, face, or airways; difficulty breathing; agitation; profuse salivation; and widespread hives or itching.</div><div><br></div><div><b>Drug and food interactions</b></div><div>There are no documented drug or food interactions with Credelio for Dogs.</div><div>Contact your veterinarian if your pet experiences any unusual reactions when different medications are given together.</div><div><br></div><div>Please ensure your veterinarian is aware of all medications and supplements that your pet is currently receiving. Your veterinarian may prescribe multiple medications, even if a potential drug interaction may occur. In these instances, your veterinarian may adjust the dosages or monitor your pet more closely.</div><div><br></div><div><b>Adverse reactions</b></div><div>If you are concerned that your pet has experienced an adverse reaction to this medication, please contact the manufacturer Elanco US at 1-888-545-5973 or Vetsource Pet Owner Care at 877-738-4443.</div><div><br></div><div><b>Overdose</b></div><div>If you have any reason to suspect an overdose, call your doctor/veterinarian or the appropriate poison control resource immediately.</div><div><br></div><div>For humans:</div><div>The national toll-free Poison Help line, 1-800-222-1222, will connect you to your local poison center in case of emergency. This service is available nationwide and in most U.S. territories.</div><div><br></div><div>For animals:</div><div>The ASPCA Animal Poison Control Center is available 24 hours a day, 365 days a year at 888-426-4435.</div><div>Pet Poison Helpline&reg; also provides a 24/7 animal poison control service at 855-764-7661.</div><div><br></div><div><i>*Please note: this information is for third-party services and is provided for convenience in case of potential poison-related emergencies. There may be consultation fee for these services.</i></div><div><br></div><div><b>Disclaimer</b></div><div><b>The content provided on this page is NOT medical advice.</b></div><div>All content, including the images and product description above, is intended for general informational purposes only and should not be considered a substitute for professional veterinary consultation, diagnosis, or treatment.</div><div>Consult your veterinarian for complete information about this product and how it fits into your pet's individual treatment plan.</div><div><br><hr></div><div><i>Last revised: 8/19/2025</i></div>"
            }
        },
        {
            "id": 197580,
            "pharmainfo": {
                "html": "<div><b>Product details</b></div><div>Credelio (lotilaner) for Dogs is a beef-flavored, chewable tablet administered once per month to kill adult fleas, treat and prevent flea infestations, and treat and control tick infestations (lone star tick, American dog tick, black-legged tick, and brown dog tick) in dogs and puppies 8 weeks of age and older, and weighing 4.4 pounds or greater.</div><ul><li>Tick and flea treatment &amp; infestation prevention for dogs 8 weeks of age and older, and weighing 4.4 pounds or greater</li><li>Fast-acting ingredients start killing <i>Ixodes ricinus</i> ticks &amp; adult fleas in just 4 hours</li><li>Kills 100% of fleas in 12 hours &amp; stays effective for 30 days</li><li>Easy to give your dog; no greasy, messy application</li><li>Small, beef-flavored chewable tablet accepted by 100% of dogs tested (Karadzovska D, Chappell K, Coble S, et al. A randomized, controlled field study to assess the efficacy and safety of lotilaner flavored chewable tablets (Credelio&trade;) in eliminating fleas in client-owned dogs in the USA. Parasite Vector. 2017;10(1):528.)</li></ul><div><br></div><div><b>Product sourced directly from the manufacturer or their approved distributor. Guaranteed genuine product backed by the manufacturer.</b></div><div><br><hr></div><div><br></div><div><b>For</b></div><div>Dogs (8 weeks of age and older)</div><div><br></div><div><b>Active ingredient(s)</b></div><div>Lotilaner</div><div><br></div><div><b>Inactive ingredients</b></div><div>Complete inactive ingredients list not provided by manufacturer.</div><div><br></div><div><b>Brand name</b></div><div>Credelio for Dogs</div><div><br></div><div><b>Drug class</b></div><div>Isoxazoline ectoparasiticide</div><div><br></div><div><b>Product flavoring</b></div><div>Credelio for Dogs is “beef” flavored.</div><div><i>*Contains pork liver, soy, barley, wheat, lactose (does not contain actual beef)</i></div><div><br></div><div><b>Manufacturer</b></div><div>Elanco</div><div><br></div><div><b>Product strength &amp; size</b></div><div><style>    table, th, td {        border: 1px solid;        border-collapse: collapse;        padding: 8px;        text-align: center;    }</style><table style=\"width: max(75%, min(319px, 100%))\"><tbody><tr><th><b>Weight range</b></th><th><b>Lotilaner (per chewable tablet)</b></th><th><b>Chewable tablets administered</b></th></tr><tr><td>4.4 to 6 lbs</td><td>56.25 mg</td><td>One</td></tr><tr><td>6.1 to 12 lbs</td><td>112.5 mg</td><td>One</td></tr><tr><td>12.1 to 25 lbs</td><td>225 mg</td><td>One</td></tr><tr><td>25.1 to 50 lbs</td><td>450 mg</td><td>One</td></tr><tr><td>50.1 to 100* lbs</td><td>900 mg</td><td>One</td></tr></tbody></table></div><div><br></div><div>*For dogs over 100 lbs, administer the appropriate combination of chewable tablets to cover your pet&rsquo;s body weight.</div><div><br><hr></div><div><br></div><div><b>Usage</b></div><div><i>*For complete product information, please review the full prescribing information in the manufacturer package insert.</i></div><div><br></div><div>Manufacturer Dosage and Administration:</div><div>Credelio is given orally once a month, at the minimum dosage of 9 mg/lb (20 mg/kg).</div><div>Credelio must be administered with food or given within 30 minutes of feeding.</div><div>Treatment with Credelio can begin at any time of the year and can continue year-round without interruption.</div><div><br></div><div><b>Missed doses</b></div><div>If a dose is missed, administer Credelio with food and resume a monthly dosing schedule to minimize the opportunity for tick and flea re-infestations. Consult your veterinarian about any concerns you may have about ticks and fleas due to the late/missed dose.</div><div><br></div><div><b>Storage</b></div><div>Store in a cool, dry place at a controlled room temperature (59 to 77&deg;F, excursions permitted between 41 to 104&deg;F). Keep out of the reach of children and pets. Tablets should remain sealed in their original packaging and should only be taken out of the blister pack at the time of dosing. Store away from heat and direct sunlight.</div><div>Do not store in the bathroom, near the kitchen sink, or in damp places. The medicine may break down if exposed to heat or moisture.</div><div><br></div><div><hr></div><div><br></div><div><b>Side effects</b></div><div>Credelio is generally well tolerated, and side effects are considered uncommon when given at the recommended dosage. The most common side effects of this medication are vomiting, diarrhea, decreased appetite, weight loss, elevated blood urea nitrogen (BUN), and increased urination.</div><div><br></div><div>Contact your veterinarian immediately if your pet experiences persistent vomiting, complete loss of appetite, or if you notice your pet has a seizure, tremors, extreme weakness, or decreased coordination (e.g., stumbling, difficulty walking).</div><div><br></div><div>Notify your veterinarian if your pet experiences any of the effects described above, or if you notice any other side effects that are persistent or troublesome.</div><div>If you notice anything unusual, please consult your veterinarian.</div><div><br></div><div><b>Precautions</b></div><div><i>*For complete product information including warnings and precautions, please refer to the manufacturer package insert.</i></div><div><br></div><div>For oral use in dogs only- not for human use. Keep this and all drugs out of the reach of children. Keep Credelio in a secure location out of reach of dogs, cats, and other animals to prevent accidental ingestion or overdose.</div><div><br></div><div>Lotilaner is a member of the isoxazoline class. This class has been associated with neurologic adverse reactions including tremors, ataxia, and seizures. Seizures have been reported in dogs receiving isoxazoline class drugs, even in dogs without a history of seizures. Use with caution in dogs with a history of seizures or neurologic disorders.</div><div>The safe use of Credelio in breeding, pregnant, or lactating dogs has not been evaluated. Discuss the risks of using this medication with your veterinarian if your pet is in one of these groups.</div><div><br></div><div>Do not administer to animals with a known history or suspected allergy/hypersensitivity to any isoxazoline class drug, including this medication or any of its ingredients. Allergic reactions to medications may occur. Be sure to inform Vetsource and your veterinarian if your pet has any known drug sensitivities or allergies.</div><div>If your pet displays symptoms of an allergic reaction, discontinue therapy and call your veterinarian immediately or seek emergency veterinary attention. Symptoms may include (but are not limited to): swollen lips, tongue, face, or airways; difficulty breathing; agitation; profuse salivation; and widespread hives or itching.</div><div><br></div><div><b>Drug and food interactions</b></div><div>There are no documented drug or food interactions with Credelio for Dogs.</div><div>Contact your veterinarian if your pet experiences any unusual reactions when different medications are given together.</div><div><br></div><div>Please ensure your veterinarian is aware of all medications and supplements that your pet is currently receiving. Your veterinarian may prescribe multiple medications, even if a potential drug interaction may occur. In these instances, your veterinarian may adjust the dosages or monitor your pet more closely.</div><div><br></div><div><b>Adverse reactions</b></div><div>If you are concerned that your pet has experienced an adverse reaction to this medication, please contact the manufacturer Elanco US at 1-888-545-5973 or Vetsource Pet Owner Care at 877-738-4443.</div><div><br></div><div><b>Overdose</b></div><div>If you have any reason to suspect an overdose, call your doctor/veterinarian or the appropriate poison control resource immediately.</div><div><br></div><div>For humans:</div><div>The national toll-free Poison Help line, 1-800-222-1222, will connect you to your local poison center in case of emergency. This service is available nationwide and in most U.S. territories.</div><div><br></div><div>For animals:</div><div>The ASPCA Animal Poison Control Center is available 24 hours a day, 365 days a year at 888-426-4435.</div><div>Pet Poison Helpline&reg; also provides a 24/7 animal poison control service at 855-764-7661.</div><div><br></div><div><i>*Please note: this information is for third-party services and is provided for convenience in case of potential poison-related emergencies. There may be consultation fee for these services.</i></div><div><br></div><div><b>Disclaimer</b></div><div><b>The content provided on this page is NOT medical advice.</b></div><div>All content, including the images and product description above, is intended for general informational purposes only and should not be considered a substitute for professional veterinary consultation, diagnosis, or treatment.</div><div>Consult your veterinarian for complete information about this product and how it fits into your pet's individual treatment plan.</div><div><br><hr></div><div><i>Last revised: 8/19/2025</i></div>"
            }
        },
        {
            "id": 197581,
            "pharmainfo": null
        },
        {
            "id": 197582,
            "pharmainfo": null
        },
        {
            "id": 197583,
            "pharmainfo": null
        },
        {
            "id": 197584,
            "pharmainfo": null
        },
        {
            "id": 197585,
            "pharmainfo": null
        },
        {
            "id": 197586,
            "pharmainfo": null
        },
        {
            "id": 197587,
            "pharmainfo": null
        },
        {
            "id": 197588,
            "pharmainfo": null
        },
        {
            "id": 197589,
            "pharmainfo": null
        },
        {
            "id": 197590,
            "pharmainfo": null
        },
        {
            "id": 197591,
            "pharmainfo": null
        },
        {
            "id": 197592,
            "pharmainfo": null
        },
        {
            "id": 197593,
            "pharmainfo": null
        },
        {
            "id": 197594,
            "pharmainfo": null
        },
        {
            "id": 197595,
            "pharmainfo": null
        },
        {
            "id": 197596,
            "pharmainfo": null
        },
        {
            "id": 197597,
            "pharmainfo": null
        },
        {
            "id": 197598,
            "pharmainfo": null
        },
        {
            "id": 197599,
            "pharmainfo": null
        },
        {
            "id": 197600,
            "pharmainfo": null
        },
        {
            "id": 197601,
            "pharmainfo": null
        },
        {
            "id": 197602,
            "pharmainfo": null
        },
        {
            "id": 197603,
            "pharmainfo": null
        },
        {
            "id": 197604,
            "pharmainfo": null
        },
        {
            "id": 197605,
            "pharmainfo": null
        },
        {
            "id": 197606,
            "pharmainfo": null
        },
        {
            "id": 197607,
            "pharmainfo": null
        },
        {
            "id": 197608,
            "pharmainfo": null
        },
        {
            "id": 197609,
            "pharmainfo": null
        },
        {
            "id": 197610,
            "pharmainfo": {
                "html": "<strong><p>Certain states apply restrictions to the dispensing of this medication, including IA, LA, and OR. This item CANNOT be shipped to Idaho.</strong></p><br>\r\n\r\n<strong>What is Proin ER?</strong><br>\r\nProin ER is a prescription medication used in the management of urinary incontinence in dogs.\r\n<p><strong>Who is it for?</strong><br>\r\nProin ER is for dogs.\r\n\r\n<p><strong>What are the benefits?</strong><br>\r\n<table cellpadding=\"4\" cellspacing=\"0\" border=\"0\">\r\n     <tr valign=\"top\">\r\n          <td><strong>*</strong></td>\r\n\t  <td>An effective prescription approach to help manage urinary incontinence in dogs </td>\r\n     </tr>\r\n     <tr valign=\"top\">\r\n          <td><strong>*</strong></span></td>\r\n\t  <td>Ideal solution for dogs who \"dribble\" on their beds or other places due to incontinence</td>\r\n     </tr>\r\n     <tr valign=\"top\">\r\n          <td><strong>*</strong></td>\r\n\t  <td>Helps tighten the urethral sphincter, which helps to control urine leakage</td>\r\n     </tr>\r\n</table></p>\r\n\r\n\r\n\r\n<p><strong>How does Proin ER work?</strong><br>\r\nProin ER contains the active ingredient phenylpropanolamine, which works by tightening the bladder sphincter muscle to help control urine leakage.\r\n\r\n<!---\r\n<p><strong>Is there a generic equivalent available?</strong><br>\r\nNo\r\n<p><strong>How is it given?</strong><br>\r\nProin ER tablets are given with food. Give Proin ER exactly as directed by the veterinarian. If you do not understand the directions, ask the pharmacist or veterinarian to explain them to you.\r\n\r\n<p><strong>What results can I expect?</strong><br>\r\nProin ER will not cure the incontinence, but will help manage it. It may take several days of treatment to see the full effect of the medication. To remain effective, Proin ER must be given continually. Stopping treatment will cause recurrence of the symptoms.\r\n\r\n\r\n<p><strong>What form(s) does it come in?</strong><br>\r\nProin ER comes in chewable tablets\r\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\r\n\t\t<p><strong>Brand Name</strong><br>\r\nProin ER\r\n\r\n<p><strong>Pronunciation</strong><br>\r\nPROE-inn\r\n\r\n\r\n<p><strong>Common Drug Name</strong><br>\r\nPhenylpropanolamine\r\n\r\n<p><strong>What should I discuss with my veterinarian while considering Proin ER?</strong><br>\r\nTalk to your veterinarian about what type of outcome is expected. Have your veterinarian explain the other treatment options that may be available to treat your pet's condition.\r\n<p>Tell your veterinarian if your pet has glaucoma, enlarged prostate, hyperthyroidism, diabetes mellitus, heart problems, high blood pressure; is pregnant; or if you intend to breed your pet.</p>\r\n<p>Notify your veterinarian of any other medications or supplements your pet is taking. Also tell your veterinarian if your pet has had any reactions to previous medications.</p>\r\n\r\n\r\n\r\n<p><strong>What should I do if I miss a dose?</strong><br>\r\nIf you miss a dose, give it as soon as you remember. If it is almost time for the next dose, skip the one you missed and go back to the regular schedule. Do not give two doses at once.\r\n\r\n<p><strong>What is the most important information I should know?</strong><br>\r\nGive Proin ER exactly as your veterinarian prescribes. Missed doses could result in a recurrence of symptoms. \r\n\r\n<p>Contact your veterinarian if your pet becomes restless, irritable or the incontinence persists or gets worse.</p>\r\n\r\n\r\n<p><strong>Who should not take it?</strong><br>\r\nNot for use in animals hypersensitive (allergic) to it. Do not use in animals with glaucoma, enlarged prostate, hyperthyroidism, diabetes mellitus, heart problems, or high blood pressure.\r\n\r\n<p>Do not use in pregnant, or lactating animals (female animals nursing their young).</p>\r\n\r\n\r\n<p><strong>What side effects may be seen when taking Proin ER?</strong><br>\r\nMay see restlessness or irritability. You may also see increased heart rate, increased blood pressure, or loss of appetite. If you see any of these signs, or the incontinence persists or worsens, contact your veterinarian.\r\n\r\n<p>If your pet experiences an allergic reaction to the medication, signs may include facial swelling, hives,scratching, sudden onset of diarrhea, vomiting, shock, seizures, pale gums, cold limbs, or coma. If you observe any of these signs, contact your veterinarian immediately.\r\n</p>\r\n\r\n<p><strong>How is it stored?</strong><br>\r\nStore Proin ER at room temperature away from moisture and heat. Keep this medication away from children and pets.\r\n\r\n<p><strong>What should I do if I know of or suspect there has been an overdose?</strong><br>\r\nShould overdose occur, you may see loss of appetite, lethargy, increased blood pressure, increased heart rate, weakness, collapse, rapid respiration, pale gums, heart failure, seizures, or coma.\r\n\r\n<p>If you know or suspect your pet has had an overdose, or if you observe any of these signs in your pet, contact your veterinarian immediately.</p>\r\n\r\n\r\n<p><strong>What should I avoid when giving my pet Proin ER?</strong><br>\r\nConsult your veterinarian before using Proin ER with any other medications, including vitamins and\r\nsupplements, ephedrine, epinephrine, or beta-blockers (like propranolol), since interactions may occur.\r\n\r\n<p>Do not use with or within 2-5 weeks of using monoamine oxidase inhibitors (MAOIs) such as selegiline (deprenyl, Anipryl), isoniazid, or amitraz (an ingredient in some flea collars and in Mitaban, used to treat mange). Consult your veterinarian before using other medications or tick collars along with Proin ER.\r\n</p>\r\n<p>There is an increased risk of high blood pressure if used with non-steroidal anti-inflammatory (NSAID) drugs (e.g., aspirin, carprofen (Novox or Rimadyl), etodolac (EtoGesic), meloxicam (Metacam), firocoxib (Previcox), deracoxib (Deramaxx), tepoxalin (Zubrin) or tricyclic antidepressants (e.g., amitriptyline or clomipramine). There is also an increased risk of irregular heart rhythms if used with digoxin.\r\n</p>"
            }
        },
        {
            "id": 197611,
            "pharmainfo": {
                "html": "<div><b>Product details</b></div><div>Proin ER (phenylpropanolamine hydrochloride extended-release) Tablets contain phenylpropanolamine, a sympathomimetic amine primarily used to control urinary incontinence (leakage) in dogs. <b>This product is an extended-release tablet formulation (not chewable/immediate-release).</b></div><div><i>*Note: Proin ER Tablets should not be confused (and are not typically considered interchangeable) with Proin Chewable (immediate-release) Tablets.</i></div><ul><li>FDA-approved: The only once-a-day, FDA-approved medication for the control of urinary incontinence due to urethral sphincter hypotonus in dogs.</li><li>1x per day: One extended-release tablet per day can be conveniently given with food.</li><li>Accurate dosing: Available in four weight-based strengths for accurate dosage of virtually any sized dog weighing 10 pounds or more.</li><li>Enticing flavor: Delicious tablets improve compliance and make treatment easy.</li><li>Convenient packaging: 30 ct. &amp; 90 ct. bottles are conveniently sized for storage and dosing.</li></ul><div><br></div><div><i>Proin ER (phenylpropanolamine) is a controlled substance in the following states: AR, IA, LA, MS, WV.</i></div><div><i>All electronically prescribed orders shipping to these states will require secondary verbal or faxed authorization from the prescriber prior to dispensing this medication.</i></div><div><i>The following states require the <b>pet owner&rsquo;s</b> date of birth to be on file prior to dispensing: AR, IN, LA, MS, WV.</i></div><div><br></div><div><b>Product sourced directly from the manufacturer or their approved distributor. Guaranteed genuine product backed by the manufacturer.</b></div><div><br><hr></div><div><br></div><div><b>For</b></div><div>Dogs</div><div><br></div><div><b>Active ingredient(s)</b></div><div>Phenylpropanolamine hydrochloride</div><div><br></div><div><b>Inactive ingredients</b></div><div>Complete inactive ingredients list not provided by manufacturer.</div><div><br></div><div><b>Brand name</b></div><div>Proin ER Tablets</div><div><br></div><div><b>Drug class</b></div><div>Sympathomimetic amine</div><div><br></div><div><b>Product flavoring</b></div><div>Proin ER Tablets are poultry liver flavored.</div><div><i>*Contains hydrolyzed chicken, soy, yeast</i></div><div><br></div><div><b>Manufacturer</b></div><div>PRN Pharmacal</div><div><br></div><div><b>Product strength &amp; size</b></div><div>Proin ER <b>extended-release tablets</b> may be available in multiple strengths and/or sizes. Please ensure the selected product and package size are appropriate for your pet, as recommended by your veterinarian.</div><div>For current availability, please refer to the product selection above.</div><div><br><hr></div><div><br></div><div><b>Usage</b></div><div><i>*For complete product information, please review the full prescribing information in the manufacturer package insert.</i></div><div><br></div><div>Proin ER Tablets should be given orally as directed by your veterinarian. Please consult your veterinarian before making any changes or discontinuing the prescribed dosing schedule.</div><div>Proin ER Tablets should be given with food. Do not split or crush the tablet.</div><div>Ensure your pet always has access to fresh, clean drinking water while taking this medication.</div><div><br></div><div><b>Missed doses</b></div><div>Administer the dose as soon as possible. If it is almost time for the next dose, skip the missed dose and continue with the regular schedule. Do not give more medication than prescribed or two doses at once.</div><div><br></div><div><b>Storage</b></div><div>Store in a cool, dry place at a controlled room temperature (68 to 77&deg;F, excursions permitted between 59 and 104&deg;F). Keep the container tightly closed when not in use and out of the reach of children and pets. Store away from heat and direct sunlight. Do not store in the bathroom, near the kitchen sink, or in damp places. The medicine may break down if exposed to heat or moisture.</div><div><br></div><div><hr></div><div><br></div><div><b>Side effects</b></div><div>The most common side effects of this medication include (but may not be limited to) increased thirst, vomiting, diarrhea, decreased appetite, lethargy, and restlessness.</div><div><br></div><div>Contact your veterinarian immediately if your pet experiences complete loss of appetite, significant weight loss, seizures or collapse, abnormal gait (difficulty walking), extreme behavioral changes (e.g., anxiety, irritability, or aggression), vocalization, or if your pet displays any signs of an extreme increase in blood pressure (including disorientation, decreased coordination, blood in the urine, bloody nose, or sudden blindness).</div><div><br></div><div>Notify your veterinarian if your pet experiences any of the effects described above, or if you notice any other side effects that are persistent or troublesome.</div><div>If you notice anything unusual, please consult your veterinarian.</div><div><br></div><div><b>Precautions</b></div><div><i>*For complete product information including warnings and precautions, please refer to the manufacturer package insert.</i></div><div><br></div><div>For oral use in dogs only- not for human use. Keep out of reach of children. Consult a physician in case of accidental ingestion by humans. Keep PROIN ER in a secure location out of the reach of dogs, cats and other animals to prevent accidental ingestion or overdose.</div><div><br></div><div>PROIN ER may cause increased thirst; therefore, provide ample fresh water. Do not split or crush tablets.</div><div>Instances of dogs chewing through closed vials of PROIN and eating the vial contents have been reported, in some cases resulting in overdose. Keep the product in a secure storage area out of the reach of pets to prevent accidental ingestion or overdose, as dogs may willingly consume more than the recommended dosage of PROIN ER tablets. Contact your veterinarian immediately if your dog ingests more tablets than prescribed or if other pets ingest PROIN ER.</div><div>Proin ER may mask signs of incontinence due to urinary tract infection. PROIN ER is not effective in dogs with incontinence due to neurologic disease or malformations.</div><div>PROIN ER may cause hypertension; therefore, use with caution in dogs with preexisting heart disease, hypertension, liver disease, kidney insufficiency, diabetes, glaucoma, and conditions with a predilection for hypertension (e.g., hyperthyroidism). Use with caution in dogs receiving sympathomimetic drugs, tricyclic antidepressants, or monoamine oxidase inhibitors as increased toxicity may result.</div><div>Because this medication should NOT be used within at least 2 weeks of any monoamine oxidase inhibitor (e.g., selegiline, amitraz), it is NOT compatible with flea and tick collars that contain amitraz as an active ingredient. If your pet is currently using one of these collars, consult your veterinarian before starting this medication.</div><div>The safe use of PROIN ER has not been evaluated in dogs that are intended for breeding, or that are pregnant or lactating. Discuss the risks of using this medication with your veterinarian prior to use if your pet is in one of these groups.</div><div><br></div><div>Do not administer to animals with a known history or suspected allergy/hypersensitivity to this medication or any of its ingredients. Allergic reactions to medications may occur. Be sure to inform Vetsource and your veterinarian if your pet has any known drug sensitivities or allergies.</div><div>If your pet displays symptoms of an allergic reaction, discontinue therapy and call your veterinarian immediately or seek emergency veterinary attention. Symptoms may include (but are not limited to): swollen lips, tongue, face, or airways; difficulty breathing; agitation; profuse salivation; and widespread hives or itching.</div><div><br></div><div><b>Drug and food interactions</b></div><div>The following drugs* may have potential interactions with this medication: alpha-1 antagonists (e.g., prazosin), inhaled anesthetics (e.g., isoflurane), antidiabetic agents (including insulins), aspirin, blood pressure medications (e.g., amlodipine, enalapril, telmisartan), digoxin, estriol (Incurin), MAOIs (e.g., amitraz, selegiline), oxytocin, phenothiazines (e.g., acepromazine), potassium citrate, sotalol, concurrent sympathomimetic agents (e.g., albuterol), and tricyclic antidepressants (e.g., amitriptyline, clomipramine).</div><div>*NOTE: this may not be a comprehensive list. Contact your veterinarian if your pet experiences any unusual reactions when different medications are given together.</div><div><br></div><div>Please ensure your veterinarian is aware of all medications and supplements that your pet is currently receiving. Your veterinarian may prescribe multiple medications, even if a potential drug interaction may occur. In these instances, your veterinarian may adjust the dosages or monitor your pet more closely.</div><div><br></div><div><b>Adverse reactions</b></div><div>If you are concerned that your pet has experienced an adverse reaction to this medication, please contact the manufacturer PRN Pharmacal at 850-476-9462 Vetsource Pet Owner Care at 877-738-4443.</div><div><br></div><div><b>Overdose</b></div><div>If you have any reason to suspect an overdose, call your doctor/veterinarian or the appropriate poison control resource immediately.</div><div><br></div><div>For humans:</div><div>The national toll-free Poison Help line, 1-800-222-1222, will connect you to your local poison center in case of emergency. This service is available nationwide and in most U.S. territories.</div><div><br></div><div>For animals:</div><div>The ASPCA Animal Poison Control Center is available 24 hours a day, 365 days a year at 888-426-4435.</div><div>Pet Poison Helpline&reg; also provides a 24/7 animal poison control service at 855-764-7661.</div><div><br></div><div><i>*Please note: this information is for third-party services and is provided for convenience in case of potential poison-related emergencies. There may be consultation fee for these services.</i></div><div><br></div><div><b>Disclaimer</b></div><div><b>The content provided on this page is NOT medical advice.</b></div><div>All content, including the images and product description above, is intended for general informational purposes only and should not be considered a substitute for professional veterinary consultation, diagnosis, or treatment.</div><div>Consult your veterinarian for complete information about this product and how it fits into your pet's individual treatment plan.</div><div><br><hr></div><div><i>Last revised: 8/19/2025</i></div>"
            }
        },
        {
            "id": 197612,
            "pharmainfo": {
                "html": "<div><b>Product details</b></div><div>Proin ER (phenylpropanolamine hydrochloride extended-release) Tablets contain phenylpropanolamine, a sympathomimetic amine primarily used to control urinary incontinence (leakage) in dogs. <b>This product is an extended-release tablet formulation (not chewable/immediate-release).</b></div><div><i>*Note: Proin ER Tablets should not be confused (and are not typically considered interchangeable) with Proin Chewable (immediate-release) Tablets.</i></div><ul><li>FDA-approved: The only once-a-day, FDA-approved medication for the control of urinary incontinence due to urethral sphincter hypotonus in dogs.</li><li>1x per day: One extended-release tablet per day can be conveniently given with food.</li><li>Accurate dosing: Available in four weight-based strengths for accurate dosage of virtually any sized dog weighing 10 pounds or more.</li><li>Enticing flavor: Delicious tablets improve compliance and make treatment easy.</li><li>Convenient packaging: 30 ct. &amp; 90 ct. bottles are conveniently sized for storage and dosing.</li></ul><div><br></div><div><i>Proin ER (phenylpropanolamine) is a controlled substance in the following states: AR, IA, LA, MS, WV.</i></div><div><i>All electronically prescribed orders shipping to these states will require secondary verbal or faxed authorization from the prescriber prior to dispensing this medication.</i></div><div><i>The following states require the <b>pet owner&rsquo;s</b> date of birth to be on file prior to dispensing: AR, IN, LA, MS, WV.</i></div><div><br></div><div><b>Product sourced directly from the manufacturer or their approved distributor. Guaranteed genuine product backed by the manufacturer.</b></div><div><br><hr></div><div><br></div><div><b>For</b></div><div>Dogs</div><div><br></div><div><b>Active ingredient(s)</b></div><div>Phenylpropanolamine hydrochloride</div><div><br></div><div><b>Inactive ingredients</b></div><div>Complete inactive ingredients list not provided by manufacturer.</div><div><br></div><div><b>Brand name</b></div><div>Proin ER Tablets</div><div><br></div><div><b>Drug class</b></div><div>Sympathomimetic amine</div><div><br></div><div><b>Product flavoring</b></div><div>Proin ER Tablets are poultry liver flavored.</div><div><i>*Contains hydrolyzed chicken, soy, yeast</i></div><div><br></div><div><b>Manufacturer</b></div><div>PRN Pharmacal</div><div><br></div><div><b>Product strength &amp; size</b></div><div>Proin ER <b>extended-release tablets</b> may be available in multiple strengths and/or sizes. Please ensure the selected product and package size are appropriate for your pet, as recommended by your veterinarian.</div><div>For current availability, please refer to the product selection above.</div><div><br><hr></div><div><br></div><div><b>Usage</b></div><div><i>*For complete product information, please review the full prescribing information in the manufacturer package insert.</i></div><div><br></div><div>Proin ER Tablets should be given orally as directed by your veterinarian. Please consult your veterinarian before making any changes or discontinuing the prescribed dosing schedule.</div><div>Proin ER Tablets should be given with food. Do not split or crush the tablet.</div><div>Ensure your pet always has access to fresh, clean drinking water while taking this medication.</div><div><br></div><div><b>Missed doses</b></div><div>Administer the dose as soon as possible. If it is almost time for the next dose, skip the missed dose and continue with the regular schedule. Do not give more medication than prescribed or two doses at once.</div><div><br></div><div><b>Storage</b></div><div>Store in a cool, dry place at a controlled room temperature (68 to 77&deg;F, excursions permitted between 59 and 104&deg;F). Keep the container tightly closed when not in use and out of the reach of children and pets. Store away from heat and direct sunlight. Do not store in the bathroom, near the kitchen sink, or in damp places. The medicine may break down if exposed to heat or moisture.</div><div><br></div><div><hr></div><div><br></div><div><b>Side effects</b></div><div>The most common side effects of this medication include (but may not be limited to) increased thirst, vomiting, diarrhea, decreased appetite, lethargy, and restlessness.</div><div><br></div><div>Contact your veterinarian immediately if your pet experiences complete loss of appetite, significant weight loss, seizures or collapse, abnormal gait (difficulty walking), extreme behavioral changes (e.g., anxiety, irritability, or aggression), vocalization, or if your pet displays any signs of an extreme increase in blood pressure (including disorientation, decreased coordination, blood in the urine, bloody nose, or sudden blindness).</div><div><br></div><div>Notify your veterinarian if your pet experiences any of the effects described above, or if you notice any other side effects that are persistent or troublesome.</div><div>If you notice anything unusual, please consult your veterinarian.</div><div><br></div><div><b>Precautions</b></div><div><i>*For complete product information including warnings and precautions, please refer to the manufacturer package insert.</i></div><div><br></div><div>For oral use in dogs only- not for human use. Keep out of reach of children. Consult a physician in case of accidental ingestion by humans. Keep PROIN ER in a secure location out of the reach of dogs, cats and other animals to prevent accidental ingestion or overdose.</div><div><br></div><div>PROIN ER may cause increased thirst; therefore, provide ample fresh water. Do not split or crush tablets.</div><div>Instances of dogs chewing through closed vials of PROIN and eating the vial contents have been reported, in some cases resulting in overdose. Keep the product in a secure storage area out of the reach of pets to prevent accidental ingestion or overdose, as dogs may willingly consume more than the recommended dosage of PROIN ER tablets. Contact your veterinarian immediately if your dog ingests more tablets than prescribed or if other pets ingest PROIN ER.</div><div>Proin ER may mask signs of incontinence due to urinary tract infection. PROIN ER is not effective in dogs with incontinence due to neurologic disease or malformations.</div><div>PROIN ER may cause hypertension; therefore, use with caution in dogs with preexisting heart disease, hypertension, liver disease, kidney insufficiency, diabetes, glaucoma, and conditions with a predilection for hypertension (e.g., hyperthyroidism). Use with caution in dogs receiving sympathomimetic drugs, tricyclic antidepressants, or monoamine oxidase inhibitors as increased toxicity may result.</div><div>Because this medication should NOT be used within at least 2 weeks of any monoamine oxidase inhibitor (e.g., selegiline, amitraz), it is NOT compatible with flea and tick collars that contain amitraz as an active ingredient. If your pet is currently using one of these collars, consult your veterinarian before starting this medication.</div><div>The safe use of PROIN ER has not been evaluated in dogs that are intended for breeding, or that are pregnant or lactating. Discuss the risks of using this medication with your veterinarian prior to use if your pet is in one of these groups.</div><div><br></div><div>Do not administer to animals with a known history or suspected allergy/hypersensitivity to this medication or any of its ingredients. Allergic reactions to medications may occur. Be sure to inform Vetsource and your veterinarian if your pet has any known drug sensitivities or allergies.</div><div>If your pet displays symptoms of an allergic reaction, discontinue therapy and call your veterinarian immediately or seek emergency veterinary attention. Symptoms may include (but are not limited to): swollen lips, tongue, face, or airways; difficulty breathing; agitation; profuse salivation; and widespread hives or itching.</div><div><br></div><div><b>Drug and food interactions</b></div><div>The following drugs* may have potential interactions with this medication: alpha-1 antagonists (e.g., prazosin), inhaled anesthetics (e.g., isoflurane), antidiabetic agents (including insulins), aspirin, blood pressure medications (e.g., amlodipine, enalapril, telmisartan), digoxin, estriol (Incurin), MAOIs (e.g., amitraz, selegiline), oxytocin, phenothiazines (e.g., acepromazine), potassium citrate, sotalol, concurrent sympathomimetic agents (e.g., albuterol), and tricyclic antidepressants (e.g., amitriptyline, clomipramine).</div><div>*NOTE: this may not be a comprehensive list. Contact your veterinarian if your pet experiences any unusual reactions when different medications are given together.</div><div><br></div><div>Please ensure your veterinarian is aware of all medications and supplements that your pet is currently receiving. Your veterinarian may prescribe multiple medications, even if a potential drug interaction may occur. In these instances, your veterinarian may adjust the dosages or monitor your pet more closely.</div><div><br></div><div><b>Adverse reactions</b></div><div>If you are concerned that your pet has experienced an adverse reaction to this medication, please contact the manufacturer PRN Pharmacal at 850-476-9462 Vetsource Pet Owner Care at 877-738-4443.</div><div><br></div><div><b>Overdose</b></div><div>If you have any reason to suspect an overdose, call your doctor/veterinarian or the appropriate poison control resource immediately.</div><div><br></div><div>For humans:</div><div>The national toll-free Poison Help line, 1-800-222-1222, will connect you to your local poison center in case of emergency. This service is available nationwide and in most U.S. territories.</div><div><br></div><div>For animals:</div><div>The ASPCA Animal Poison Control Center is available 24 hours a day, 365 days a year at 888-426-4435.</div><div>Pet Poison Helpline&reg; also provides a 24/7 animal poison control service at 855-764-7661.</div><div><br></div><div><i>*Please note: this information is for third-party services and is provided for convenience in case of potential poison-related emergencies. There may be consultation fee for these services.</i></div><div><br></div><div><b>Disclaimer</b></div><div><b>The content provided on this page is NOT medical advice.</b></div><div>All content, including the images and product description above, is intended for general informational purposes only and should not be considered a substitute for professional veterinary consultation, diagnosis, or treatment.</div><div>Consult your veterinarian for complete information about this product and how it fits into your pet's individual treatment plan.</div><div><br><hr></div><div><i>Last revised: 8/19/2025</i></div>"
            }
        },
        {
            "id": 197613,
            "pharmainfo": {
                "html": "<strong><p>Certain states apply restrictions to the dispensing of this medication, including IA, LA, and OR. This item CANNOT be shipped to Idaho.</strong></p><br>\r\n\r\n<strong>What is Proin ER?</strong><br>\r\nProin ER is a prescription medication used in the management of urinary incontinence in dogs.\r\n<p><strong>Who is it for?</strong><br>\r\nProin ER is for dogs.\r\n\r\n<p><strong>What are the benefits?</strong><br>\r\n<table cellpadding=\"4\" cellspacing=\"0\" border=\"0\">\r\n     <tr valign=\"top\">\r\n          <td><strong>*</strong></td>\r\n\t  <td>An effective prescription approach to help manage urinary incontinence in dogs </td>\r\n     </tr>\r\n     <tr valign=\"top\">\r\n          <td><strong>*</strong></span></td>\r\n\t  <td>Ideal solution for dogs who \"dribble\" on their beds or other places due to incontinence</td>\r\n     </tr>\r\n     <tr valign=\"top\">\r\n          <td><strong>*</strong></td>\r\n\t  <td>Helps tighten the urethral sphincter, which helps to control urine leakage</td>\r\n     </tr>\r\n</table></p>\r\n\r\n\r\n\r\n<p><strong>How does Proin ER work?</strong><br>\r\nProin ER contains the active ingredient phenylpropanolamine, which works by tightening the bladder sphincter muscle to help control urine leakage.\r\n\r\n<!---\r\n<p><strong>Is there a generic equivalent available?</strong><br>\r\nNo\r\n<p><strong>How is it given?</strong><br>\r\nProin ER tablets are given with food. Give Proin ER exactly as directed by the veterinarian. If you do not understand the directions, ask the pharmacist or veterinarian to explain them to you.\r\n\r\n<p><strong>What results can I expect?</strong><br>\r\nProin ER will not cure the incontinence, but will help manage it. It may take several days of treatment to see the full effect of the medication. To remain effective, Proin ER must be given continually. Stopping treatment will cause recurrence of the symptoms.\r\n\r\n\r\n<p><strong>What form(s) does it come in?</strong><br>\r\nProin ER comes in chewable tablets\r\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\r\n\t\t<p><strong>Brand Name</strong><br>\r\nProin ER\r\n\r\n<p><strong>Pronunciation</strong><br>\r\nPROE-inn\r\n\r\n\r\n<p><strong>Common Drug Name</strong><br>\r\nPhenylpropanolamine\r\n\r\n<p><strong>What should I discuss with my veterinarian while considering Proin ER?</strong><br>\r\nTalk to your veterinarian about what type of outcome is expected. Have your veterinarian explain the other treatment options that may be available to treat your pet's condition.\r\n<p>Tell your veterinarian if your pet has glaucoma, enlarged prostate, hyperthyroidism, diabetes mellitus, heart problems, high blood pressure; is pregnant; or if you intend to breed your pet.</p>\r\n<p>Notify your veterinarian of any other medications or supplements your pet is taking. Also tell your veterinarian if your pet has had any reactions to previous medications.</p>\r\n\r\n\r\n\r\n<p><strong>What should I do if I miss a dose?</strong><br>\r\nIf you miss a dose, give it as soon as you remember. If it is almost time for the next dose, skip the one you missed and go back to the regular schedule. Do not give two doses at once.\r\n\r\n<p><strong>What is the most important information I should know?</strong><br>\r\nGive Proin ER exactly as your veterinarian prescribes. Missed doses could result in a recurrence of symptoms. \r\n\r\n<p>Contact your veterinarian if your pet becomes restless, irritable or the incontinence persists or gets worse.</p>\r\n\r\n\r\n<p><strong>Who should not take it?</strong><br>\r\nNot for use in animals hypersensitive (allergic) to it. Do not use in animals with glaucoma, enlarged prostate, hyperthyroidism, diabetes mellitus, heart problems, or high blood pressure.\r\n\r\n<p>Do not use in pregnant, or lactating animals (female animals nursing their young).</p>\r\n\r\n\r\n<p><strong>What side effects may be seen when taking Proin ER?</strong><br>\r\nMay see restlessness or irritability. You may also see increased heart rate, increased blood pressure, or loss of appetite. If you see any of these signs, or the incontinence persists or worsens, contact your veterinarian.\r\n\r\n<p>If your pet experiences an allergic reaction to the medication, signs may include facial swelling, hives,scratching, sudden onset of diarrhea, vomiting, shock, seizures, pale gums, cold limbs, or coma. If you observe any of these signs, contact your veterinarian immediately.\r\n</p>\r\n\r\n<p><strong>How is it stored?</strong><br>\r\nStore Proin ER at room temperature away from moisture and heat. Keep this medication away from children and pets.\r\n\r\n<p><strong>What should I do if I know of or suspect there has been an overdose?</strong><br>\r\nShould overdose occur, you may see loss of appetite, lethargy, increased blood pressure, increased heart rate, weakness, collapse, rapid respiration, pale gums, heart failure, seizures, or coma.\r\n\r\n<p>If you know or suspect your pet has had an overdose, or if you observe any of these signs in your pet, contact your veterinarian immediately.</p>\r\n\r\n\r\n<p><strong>What should I avoid when giving my pet Proin ER?</strong><br>\r\nConsult your veterinarian before using Proin ER with any other medications, including vitamins and\r\nsupplements, ephedrine, epinephrine, or beta-blockers (like propranolol), since interactions may occur.\r\n\r\n<p>Do not use with or within 2-5 weeks of using monoamine oxidase inhibitors (MAOIs) such as selegiline (deprenyl, Anipryl), isoniazid, or amitraz (an ingredient in some flea collars and in Mitaban, used to treat mange). Consult your veterinarian before using other medications or tick collars along with Proin ER.\r\n</p>\r\n<p>There is an increased risk of high blood pressure if used with non-steroidal anti-inflammatory (NSAID) drugs (e.g., aspirin, carprofen (Novox or Rimadyl), etodolac (EtoGesic), meloxicam (Metacam), firocoxib (Previcox), deracoxib (Deramaxx), tepoxalin (Zubrin) or tricyclic antidepressants (e.g., amitriptyline or clomipramine). There is also an increased risk of irregular heart rhythms if used with digoxin.\r\n</p>"
            }
        },
        {
            "id": 197614,
            "pharmainfo": {
                "html": "<div><b>Product details</b></div><div>Proin ER (phenylpropanolamine hydrochloride extended-release) Tablets contain phenylpropanolamine, a sympathomimetic amine primarily used to control urinary incontinence (leakage) in dogs. <b>This product is an extended-release tablet formulation (not chewable/immediate-release).</b></div><div><i>*Note: Proin ER Tablets should not be confused (and are not typically considered interchangeable) with Proin Chewable (immediate-release) Tablets.</i></div><ul><li>FDA-approved: The only once-a-day, FDA-approved medication for the control of urinary incontinence due to urethral sphincter hypotonus in dogs.</li><li>1x per day: One extended-release tablet per day can be conveniently given with food.</li><li>Accurate dosing: Available in four weight-based strengths for accurate dosage of virtually any sized dog weighing 10 pounds or more.</li><li>Enticing flavor: Delicious tablets improve compliance and make treatment easy.</li><li>Convenient packaging: 30 ct. &amp; 90 ct. bottles are conveniently sized for storage and dosing.</li></ul><div><br></div><div><i>Proin ER (phenylpropanolamine) is a controlled substance in the following states: AR, IA, LA, MS, WV.</i></div><div><i>All electronically prescribed orders shipping to these states will require secondary verbal or faxed authorization from the prescriber prior to dispensing this medication.</i></div><div><i>The following states require the <b>pet owner&rsquo;s</b> date of birth to be on file prior to dispensing: AR, IN, LA, MS, WV.</i></div><div><br></div><div><b>Product sourced directly from the manufacturer or their approved distributor. Guaranteed genuine product backed by the manufacturer.</b></div><div><br><hr></div><div><br></div><div><b>For</b></div><div>Dogs</div><div><br></div><div><b>Active ingredient(s)</b></div><div>Phenylpropanolamine hydrochloride</div><div><br></div><div><b>Inactive ingredients</b></div><div>Complete inactive ingredients list not provided by manufacturer.</div><div><br></div><div><b>Brand name</b></div><div>Proin ER Tablets</div><div><br></div><div><b>Drug class</b></div><div>Sympathomimetic amine</div><div><br></div><div><b>Product flavoring</b></div><div>Proin ER Tablets are poultry liver flavored.</div><div><i>*Contains hydrolyzed chicken, soy, yeast</i></div><div><br></div><div><b>Manufacturer</b></div><div>PRN Pharmacal</div><div><br></div><div><b>Product strength &amp; size</b></div><div>Proin ER <b>extended-release tablets</b> may be available in multiple strengths and/or sizes. Please ensure the selected product and package size are appropriate for your pet, as recommended by your veterinarian.</div><div>For current availability, please refer to the product selection above.</div><div><br><hr></div><div><br></div><div><b>Usage</b></div><div><i>*For complete product information, please review the full prescribing information in the manufacturer package insert.</i></div><div><br></div><div>Proin ER Tablets should be given orally as directed by your veterinarian. Please consult your veterinarian before making any changes or discontinuing the prescribed dosing schedule.</div><div>Proin ER Tablets should be given with food. Do not split or crush the tablet.</div><div>Ensure your pet always has access to fresh, clean drinking water while taking this medication.</div><div><br></div><div><b>Missed doses</b></div><div>Administer the dose as soon as possible. If it is almost time for the next dose, skip the missed dose and continue with the regular schedule. Do not give more medication than prescribed or two doses at once.</div><div><br></div><div><b>Storage</b></div><div>Store in a cool, dry place at a controlled room temperature (68 to 77&deg;F, excursions permitted between 59 and 104&deg;F). Keep the container tightly closed when not in use and out of the reach of children and pets. Store away from heat and direct sunlight. Do not store in the bathroom, near the kitchen sink, or in damp places. The medicine may break down if exposed to heat or moisture.</div><div><br></div><div><hr></div><div><br></div><div><b>Side effects</b></div><div>The most common side effects of this medication include (but may not be limited to) increased thirst, vomiting, diarrhea, decreased appetite, lethargy, and restlessness.</div><div><br></div><div>Contact your veterinarian immediately if your pet experiences complete loss of appetite, significant weight loss, seizures or collapse, abnormal gait (difficulty walking), extreme behavioral changes (e.g., anxiety, irritability, or aggression), vocalization, or if your pet displays any signs of an extreme increase in blood pressure (including disorientation, decreased coordination, blood in the urine, bloody nose, or sudden blindness).</div><div><br></div><div>Notify your veterinarian if your pet experiences any of the effects described above, or if you notice any other side effects that are persistent or troublesome.</div><div>If you notice anything unusual, please consult your veterinarian.</div><div><br></div><div><b>Precautions</b></div><div><i>*For complete product information including warnings and precautions, please refer to the manufacturer package insert.</i></div><div><br></div><div>For oral use in dogs only- not for human use. Keep out of reach of children. Consult a physician in case of accidental ingestion by humans. Keep PROIN ER in a secure location out of the reach of dogs, cats and other animals to prevent accidental ingestion or overdose.</div><div><br></div><div>PROIN ER may cause increased thirst; therefore, provide ample fresh water. Do not split or crush tablets.</div><div>Instances of dogs chewing through closed vials of PROIN and eating the vial contents have been reported, in some cases resulting in overdose. Keep the product in a secure storage area out of the reach of pets to prevent accidental ingestion or overdose, as dogs may willingly consume more than the recommended dosage of PROIN ER tablets. Contact your veterinarian immediately if your dog ingests more tablets than prescribed or if other pets ingest PROIN ER.</div><div>Proin ER may mask signs of incontinence due to urinary tract infection. PROIN ER is not effective in dogs with incontinence due to neurologic disease or malformations.</div><div>PROIN ER may cause hypertension; therefore, use with caution in dogs with preexisting heart disease, hypertension, liver disease, kidney insufficiency, diabetes, glaucoma, and conditions with a predilection for hypertension (e.g., hyperthyroidism). Use with caution in dogs receiving sympathomimetic drugs, tricyclic antidepressants, or monoamine oxidase inhibitors as increased toxicity may result.</div><div>Because this medication should NOT be used within at least 2 weeks of any monoamine oxidase inhibitor (e.g., selegiline, amitraz), it is NOT compatible with flea and tick collars that contain amitraz as an active ingredient. If your pet is currently using one of these collars, consult your veterinarian before starting this medication.</div><div>The safe use of PROIN ER has not been evaluated in dogs that are intended for breeding, or that are pregnant or lactating. Discuss the risks of using this medication with your veterinarian prior to use if your pet is in one of these groups.</div><div><br></div><div>Do not administer to animals with a known history or suspected allergy/hypersensitivity to this medication or any of its ingredients. Allergic reactions to medications may occur. Be sure to inform Vetsource and your veterinarian if your pet has any known drug sensitivities or allergies.</div><div>If your pet displays symptoms of an allergic reaction, discontinue therapy and call your veterinarian immediately or seek emergency veterinary attention. Symptoms may include (but are not limited to): swollen lips, tongue, face, or airways; difficulty breathing; agitation; profuse salivation; and widespread hives or itching.</div><div><br></div><div><b>Drug and food interactions</b></div><div>The following drugs* may have potential interactions with this medication: alpha-1 antagonists (e.g., prazosin), inhaled anesthetics (e.g., isoflurane), antidiabetic agents (including insulins), aspirin, blood pressure medications (e.g., amlodipine, enalapril, telmisartan), digoxin, estriol (Incurin), MAOIs (e.g., amitraz, selegiline), oxytocin, phenothiazines (e.g., acepromazine), potassium citrate, sotalol, concurrent sympathomimetic agents (e.g., albuterol), and tricyclic antidepressants (e.g., amitriptyline, clomipramine).</div><div>*NOTE: this may not be a comprehensive list. Contact your veterinarian if your pet experiences any unusual reactions when different medications are given together.</div><div><br></div><div>Please ensure your veterinarian is aware of all medications and supplements that your pet is currently receiving. Your veterinarian may prescribe multiple medications, even if a potential drug interaction may occur. In these instances, your veterinarian may adjust the dosages or monitor your pet more closely.</div><div><br></div><div><b>Adverse reactions</b></div><div>If you are concerned that your pet has experienced an adverse reaction to this medication, please contact the manufacturer PRN Pharmacal at 850-476-9462 Vetsource Pet Owner Care at 877-738-4443.</div><div><br></div><div><b>Overdose</b></div><div>If you have any reason to suspect an overdose, call your doctor/veterinarian or the appropriate poison control resource immediately.</div><div><br></div><div>For humans:</div><div>The national toll-free Poison Help line, 1-800-222-1222, will connect you to your local poison center in case of emergency. This service is available nationwide and in most U.S. territories.</div><div><br></div><div>For animals:</div><div>The ASPCA Animal Poison Control Center is available 24 hours a day, 365 days a year at 888-426-4435.</div><div>Pet Poison Helpline&reg; also provides a 24/7 animal poison control service at 855-764-7661.</div><div><br></div><div><i>*Please note: this information is for third-party services and is provided for convenience in case of potential poison-related emergencies. There may be consultation fee for these services.</i></div><div><br></div><div><b>Disclaimer</b></div><div><b>The content provided on this page is NOT medical advice.</b></div><div>All content, including the images and product description above, is intended for general informational purposes only and should not be considered a substitute for professional veterinary consultation, diagnosis, or treatment.</div><div>Consult your veterinarian for complete information about this product and how it fits into your pet's individual treatment plan.</div><div><br><hr></div><div><i>Last revised: 8/19/2025</i></div>"
            }
        },
        {
            "id": 197615,
            "pharmainfo": {
                "html": "<div><b>Product details</b></div><div>Proin ER (phenylpropanolamine hydrochloride extended-release) Tablets contain phenylpropanolamine, a sympathomimetic amine primarily used to control urinary incontinence (leakage) in dogs. <b>This product is an extended-release tablet formulation (not chewable/immediate-release).</b></div><div><i>*Note: Proin ER Tablets should not be confused (and are not typically considered interchangeable) with Proin Chewable (immediate-release) Tablets.</i></div><ul><li>FDA-approved: The only once-a-day, FDA-approved medication for the control of urinary incontinence due to urethral sphincter hypotonus in dogs.</li><li>1x per day: One extended-release tablet per day can be conveniently given with food.</li><li>Accurate dosing: Available in four weight-based strengths for accurate dosage of virtually any sized dog weighing 10 pounds or more.</li><li>Enticing flavor: Delicious tablets improve compliance and make treatment easy.</li><li>Convenient packaging: 30 ct. &amp; 90 ct. bottles are conveniently sized for storage and dosing.</li></ul><div><br></div><div><i>Proin ER (phenylpropanolamine) is a controlled substance in the following states: AR, IA, LA, MS, WV.</i></div><div><i>All electronically prescribed orders shipping to these states will require secondary verbal or faxed authorization from the prescriber prior to dispensing this medication.</i></div><div><i>The following states require the <b>pet owner&rsquo;s</b> date of birth to be on file prior to dispensing: AR, IN, LA, MS, WV.</i></div><div><br></div><div><b>Product sourced directly from the manufacturer or their approved distributor. Guaranteed genuine product backed by the manufacturer.</b></div><div><br><hr></div><div><br></div><div><b>For</b></div><div>Dogs</div><div><br></div><div><b>Active ingredient(s)</b></div><div>Phenylpropanolamine hydrochloride</div><div><br></div><div><b>Inactive ingredients</b></div><div>Complete inactive ingredients list not provided by manufacturer.</div><div><br></div><div><b>Brand name</b></div><div>Proin ER Tablets</div><div><br></div><div><b>Drug class</b></div><div>Sympathomimetic amine</div><div><br></div><div><b>Product flavoring</b></div><div>Proin ER Tablets are poultry liver flavored.</div><div><i>*Contains hydrolyzed chicken, soy, yeast</i></div><div><br></div><div><b>Manufacturer</b></div><div>PRN Pharmacal</div><div><br></div><div><b>Product strength &amp; size</b></div><div>Proin ER <b>extended-release tablets</b> may be available in multiple strengths and/or sizes. Please ensure the selected product and package size are appropriate for your pet, as recommended by your veterinarian.</div><div>For current availability, please refer to the product selection above.</div><div><br><hr></div><div><br></div><div><b>Usage</b></div><div><i>*For complete product information, please review the full prescribing information in the manufacturer package insert.</i></div><div><br></div><div>Proin ER Tablets should be given orally as directed by your veterinarian. Please consult your veterinarian before making any changes or discontinuing the prescribed dosing schedule.</div><div>Proin ER Tablets should be given with food. Do not split or crush the tablet.</div><div>Ensure your pet always has access to fresh, clean drinking water while taking this medication.</div><div><br></div><div><b>Missed doses</b></div><div>Administer the dose as soon as possible. If it is almost time for the next dose, skip the missed dose and continue with the regular schedule. Do not give more medication than prescribed or two doses at once.</div><div><br></div><div><b>Storage</b></div><div>Store in a cool, dry place at a controlled room temperature (68 to 77&deg;F, excursions permitted between 59 and 104&deg;F). Keep the container tightly closed when not in use and out of the reach of children and pets. Store away from heat and direct sunlight. Do not store in the bathroom, near the kitchen sink, or in damp places. The medicine may break down if exposed to heat or moisture.</div><div><br></div><div><hr></div><div><br></div><div><b>Side effects</b></div><div>The most common side effects of this medication include (but may not be limited to) increased thirst, vomiting, diarrhea, decreased appetite, lethargy, and restlessness.</div><div><br></div><div>Contact your veterinarian immediately if your pet experiences complete loss of appetite, significant weight loss, seizures or collapse, abnormal gait (difficulty walking), extreme behavioral changes (e.g., anxiety, irritability, or aggression), vocalization, or if your pet displays any signs of an extreme increase in blood pressure (including disorientation, decreased coordination, blood in the urine, bloody nose, or sudden blindness).</div><div><br></div><div>Notify your veterinarian if your pet experiences any of the effects described above, or if you notice any other side effects that are persistent or troublesome.</div><div>If you notice anything unusual, please consult your veterinarian.</div><div><br></div><div><b>Precautions</b></div><div><i>*For complete product information including warnings and precautions, please refer to the manufacturer package insert.</i></div><div><br></div><div>For oral use in dogs only- not for human use. Keep out of reach of children. Consult a physician in case of accidental ingestion by humans. Keep PROIN ER in a secure location out of the reach of dogs, cats and other animals to prevent accidental ingestion or overdose.</div><div><br></div><div>PROIN ER may cause increased thirst; therefore, provide ample fresh water. Do not split or crush tablets.</div><div>Instances of dogs chewing through closed vials of PROIN and eating the vial contents have been reported, in some cases resulting in overdose. Keep the product in a secure storage area out of the reach of pets to prevent accidental ingestion or overdose, as dogs may willingly consume more than the recommended dosage of PROIN ER tablets. Contact your veterinarian immediately if your dog ingests more tablets than prescribed or if other pets ingest PROIN ER.</div><div>Proin ER may mask signs of incontinence due to urinary tract infection. PROIN ER is not effective in dogs with incontinence due to neurologic disease or malformations.</div><div>PROIN ER may cause hypertension; therefore, use with caution in dogs with preexisting heart disease, hypertension, liver disease, kidney insufficiency, diabetes, glaucoma, and conditions with a predilection for hypertension (e.g., hyperthyroidism). Use with caution in dogs receiving sympathomimetic drugs, tricyclic antidepressants, or monoamine oxidase inhibitors as increased toxicity may result.</div><div>Because this medication should NOT be used within at least 2 weeks of any monoamine oxidase inhibitor (e.g., selegiline, amitraz), it is NOT compatible with flea and tick collars that contain amitraz as an active ingredient. If your pet is currently using one of these collars, consult your veterinarian before starting this medication.</div><div>The safe use of PROIN ER has not been evaluated in dogs that are intended for breeding, or that are pregnant or lactating. Discuss the risks of using this medication with your veterinarian prior to use if your pet is in one of these groups.</div><div><br></div><div>Do not administer to animals with a known history or suspected allergy/hypersensitivity to this medication or any of its ingredients. Allergic reactions to medications may occur. Be sure to inform Vetsource and your veterinarian if your pet has any known drug sensitivities or allergies.</div><div>If your pet displays symptoms of an allergic reaction, discontinue therapy and call your veterinarian immediately or seek emergency veterinary attention. Symptoms may include (but are not limited to): swollen lips, tongue, face, or airways; difficulty breathing; agitation; profuse salivation; and widespread hives or itching.</div><div><br></div><div><b>Drug and food interactions</b></div><div>The following drugs* may have potential interactions with this medication: alpha-1 antagonists (e.g., prazosin), inhaled anesthetics (e.g., isoflurane), antidiabetic agents (including insulins), aspirin, blood pressure medications (e.g., amlodipine, enalapril, telmisartan), digoxin, estriol (Incurin), MAOIs (e.g., amitraz, selegiline), oxytocin, phenothiazines (e.g., acepromazine), potassium citrate, sotalol, concurrent sympathomimetic agents (e.g., albuterol), and tricyclic antidepressants (e.g., amitriptyline, clomipramine).</div><div>*NOTE: this may not be a comprehensive list. Contact your veterinarian if your pet experiences any unusual reactions when different medications are given together.</div><div><br></div><div>Please ensure your veterinarian is aware of all medications and supplements that your pet is currently receiving. Your veterinarian may prescribe multiple medications, even if a potential drug interaction may occur. In these instances, your veterinarian may adjust the dosages or monitor your pet more closely.</div><div><br></div><div><b>Adverse reactions</b></div><div>If you are concerned that your pet has experienced an adverse reaction to this medication, please contact the manufacturer PRN Pharmacal at 850-476-9462 Vetsource Pet Owner Care at 877-738-4443.</div><div><br></div><div><b>Overdose</b></div><div>If you have any reason to suspect an overdose, call your doctor/veterinarian or the appropriate poison control resource immediately.</div><div><br></div><div>For humans:</div><div>The national toll-free Poison Help line, 1-800-222-1222, will connect you to your local poison center in case of emergency. This service is available nationwide and in most U.S. territories.</div><div><br></div><div>For animals:</div><div>The ASPCA Animal Poison Control Center is available 24 hours a day, 365 days a year at 888-426-4435.</div><div>Pet Poison Helpline&reg; also provides a 24/7 animal poison control service at 855-764-7661.</div><div><br></div><div><i>*Please note: this information is for third-party services and is provided for convenience in case of potential poison-related emergencies. There may be consultation fee for these services.</i></div><div><br></div><div><b>Disclaimer</b></div><div><b>The content provided on this page is NOT medical advice.</b></div><div>All content, including the images and product description above, is intended for general informational purposes only and should not be considered a substitute for professional veterinary consultation, diagnosis, or treatment.</div><div>Consult your veterinarian for complete information about this product and how it fits into your pet's individual treatment plan.</div><div><br><hr></div><div><i>Last revised: 8/19/2025</i></div>"
            }
        },
        {
            "id": 197616,
            "pharmainfo": {
                "html": "<strong><p>Certain states apply restrictions to the dispensing of this medication, including IA, LA, and OR. This item CANNOT be shipped to Idaho.</strong></p><br>\r\n\r\n<strong>What is Proin ER?</strong><br>\r\nProin ER is a prescription medication used in the management of urinary incontinence in dogs.\r\n<p><strong>Who is it for?</strong><br>\r\nProin ER is for dogs.\r\n\r\n<p><strong>What are the benefits?</strong><br>\r\n<table cellpadding=\"4\" cellspacing=\"0\" border=\"0\">\r\n     <tr valign=\"top\">\r\n          <td><strong>*</strong></td>\r\n\t  <td>An effective prescription approach to help manage urinary incontinence in dogs </td>\r\n     </tr>\r\n     <tr valign=\"top\">\r\n          <td><strong>*</strong></span></td>\r\n\t  <td>Ideal solution for dogs who \"dribble\" on their beds or other places due to incontinence</td>\r\n     </tr>\r\n     <tr valign=\"top\">\r\n          <td><strong>*</strong></td>\r\n\t  <td>Helps tighten the urethral sphincter, which helps to control urine leakage</td>\r\n     </tr>\r\n</table></p>\r\n\r\n\r\n\r\n<p><strong>How does Proin ER work?</strong><br>\r\nProin ER contains the active ingredient phenylpropanolamine, which works by tightening the bladder sphincter muscle to help control urine leakage.\r\n\r\n<!---\r\n<p><strong>Is there a generic equivalent available?</strong><br>\r\nNo\r\n<p><strong>How is it given?</strong><br>\r\nProin ER tablets are given with food. Give Proin ER exactly as directed by the veterinarian. If you do not understand the directions, ask the pharmacist or veterinarian to explain them to you.\r\n\r\n<p><strong>What results can I expect?</strong><br>\r\nProin ER will not cure the incontinence, but will help manage it. It may take several days of treatment to see the full effect of the medication. To remain effective, Proin ER must be given continually. Stopping treatment will cause recurrence of the symptoms.\r\n\r\n\r\n<p><strong>What form(s) does it come in?</strong><br>\r\nProin ER comes in chewable tablets\r\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\r\n\t\t<p><strong>Brand Name</strong><br>\r\nProin ER\r\n\r\n<p><strong>Pronunciation</strong><br>\r\nPROE-inn\r\n\r\n\r\n<p><strong>Common Drug Name</strong><br>\r\nPhenylpropanolamine\r\n\r\n<p><strong>What should I discuss with my veterinarian while considering Proin ER?</strong><br>\r\nTalk to your veterinarian about what type of outcome is expected. Have your veterinarian explain the other treatment options that may be available to treat your pet's condition.\r\n<p>Tell your veterinarian if your pet has glaucoma, enlarged prostate, hyperthyroidism, diabetes mellitus, heart problems, high blood pressure; is pregnant; or if you intend to breed your pet.</p>\r\n<p>Notify your veterinarian of any other medications or supplements your pet is taking. Also tell your veterinarian if your pet has had any reactions to previous medications.</p>\r\n\r\n\r\n\r\n<p><strong>What should I do if I miss a dose?</strong><br>\r\nIf you miss a dose, give it as soon as you remember. If it is almost time for the next dose, skip the one you missed and go back to the regular schedule. Do not give two doses at once.\r\n\r\n<p><strong>What is the most important information I should know?</strong><br>\r\nGive Proin ER exactly as your veterinarian prescribes. Missed doses could result in a recurrence of symptoms. \r\n\r\n<p>Contact your veterinarian if your pet becomes restless, irritable or the incontinence persists or gets worse.</p>\r\n\r\n\r\n<p><strong>Who should not take it?</strong><br>\r\nNot for use in animals hypersensitive (allergic) to it. Do not use in animals with glaucoma, enlarged prostate, hyperthyroidism, diabetes mellitus, heart problems, or high blood pressure.\r\n\r\n<p>Do not use in pregnant, or lactating animals (female animals nursing their young).</p>\r\n\r\n\r\n<p><strong>What side effects may be seen when taking Proin ER?</strong><br>\r\nMay see restlessness or irritability. You may also see increased heart rate, increased blood pressure, or loss of appetite. If you see any of these signs, or the incontinence persists or worsens, contact your veterinarian.\r\n\r\n<p>If your pet experiences an allergic reaction to the medication, signs may include facial swelling, hives,scratching, sudden onset of diarrhea, vomiting, shock, seizures, pale gums, cold limbs, or coma. If you observe any of these signs, contact your veterinarian immediately.\r\n</p>\r\n\r\n<p><strong>How is it stored?</strong><br>\r\nStore Proin ER at room temperature away from moisture and heat. Keep this medication away from children and pets.\r\n\r\n<p><strong>What should I do if I know of or suspect there has been an overdose?</strong><br>\r\nShould overdose occur, you may see loss of appetite, lethargy, increased blood pressure, increased heart rate, weakness, collapse, rapid respiration, pale gums, heart failure, seizures, or coma.\r\n\r\n<p>If you know or suspect your pet has had an overdose, or if you observe any of these signs in your pet, contact your veterinarian immediately.</p>\r\n\r\n\r\n<p><strong>What should I avoid when giving my pet Proin ER?</strong><br>\r\nConsult your veterinarian before using Proin ER with any other medications, including vitamins and\r\nsupplements, ephedrine, epinephrine, or beta-blockers (like propranolol), since interactions may occur.\r\n\r\n<p>Do not use with or within 2-5 weeks of using monoamine oxidase inhibitors (MAOIs) such as selegiline (deprenyl, Anipryl), isoniazid, or amitraz (an ingredient in some flea collars and in Mitaban, used to treat mange). Consult your veterinarian before using other medications or tick collars along with Proin ER.\r\n</p>\r\n<p>There is an increased risk of high blood pressure if used with non-steroidal anti-inflammatory (NSAID) drugs (e.g., aspirin, carprofen (Novox or Rimadyl), etodolac (EtoGesic), meloxicam (Metacam), firocoxib (Previcox), deracoxib (Deramaxx), tepoxalin (Zubrin) or tricyclic antidepressants (e.g., amitriptyline or clomipramine). There is also an increased risk of irregular heart rhythms if used with digoxin.\r\n</p>"
            }
        },
        {
            "id": 197617,
            "pharmainfo": {
                "html": "<strong><p>Certain states apply restrictions to the dispensing of this medication, including IA, LA, and OR. This item CANNOT be shipped to Idaho.</strong></p><br>\r\n\r\n<strong>What is Proin ER?</strong><br>\r\nProin ER is a prescription medication used in the management of urinary incontinence in dogs.\r\n<p><strong>Who is it for?</strong><br>\r\nProin ER is for dogs.\r\n\r\n<p><strong>What are the benefits?</strong><br>\r\n<table cellpadding=\"4\" cellspacing=\"0\" border=\"0\">\r\n     <tr valign=\"top\">\r\n          <td><strong>*</strong></td>\r\n\t  <td>An effective prescription approach to help manage urinary incontinence in dogs </td>\r\n     </tr>\r\n     <tr valign=\"top\">\r\n          <td><strong>*</strong></span></td>\r\n\t  <td>Ideal solution for dogs who \"dribble\" on their beds or other places due to incontinence</td>\r\n     </tr>\r\n     <tr valign=\"top\">\r\n          <td><strong>*</strong></td>\r\n\t  <td>Helps tighten the urethral sphincter, which helps to control urine leakage</td>\r\n     </tr>\r\n</table></p>\r\n\r\n\r\n\r\n<p><strong>How does Proin ER work?</strong><br>\r\nProin ER contains the active ingredient phenylpropanolamine, which works by tightening the bladder sphincter muscle to help control urine leakage.\r\n\r\n<!---\r\n<p><strong>Is there a generic equivalent available?</strong><br>\r\nNo\r\n<p><strong>How is it given?</strong><br>\r\nProin ER tablets are given with food. Give Proin ER exactly as directed by the veterinarian. If you do not understand the directions, ask the pharmacist or veterinarian to explain them to you.\r\n\r\n<p><strong>What results can I expect?</strong><br>\r\nProin ER will not cure the incontinence, but will help manage it. It may take several days of treatment to see the full effect of the medication. To remain effective, Proin ER must be given continually. Stopping treatment will cause recurrence of the symptoms.\r\n\r\n\r\n<p><strong>What form(s) does it come in?</strong><br>\r\nProin ER comes in chewable tablets\r\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\r\n\t\t<p><strong>Brand Name</strong><br>\r\nProin ER\r\n\r\n<p><strong>Pronunciation</strong><br>\r\nPROE-inn\r\n\r\n\r\n<p><strong>Common Drug Name</strong><br>\r\nPhenylpropanolamine\r\n\r\n<p><strong>What should I discuss with my veterinarian while considering Proin ER?</strong><br>\r\nTalk to your veterinarian about what type of outcome is expected. Have your veterinarian explain the other treatment options that may be available to treat your pet's condition.\r\n<p>Tell your veterinarian if your pet has glaucoma, enlarged prostate, hyperthyroidism, diabetes mellitus, heart problems, high blood pressure; is pregnant; or if you intend to breed your pet.</p>\r\n<p>Notify your veterinarian of any other medications or supplements your pet is taking. Also tell your veterinarian if your pet has had any reactions to previous medications.</p>\r\n\r\n\r\n\r\n<p><strong>What should I do if I miss a dose?</strong><br>\r\nIf you miss a dose, give it as soon as you remember. If it is almost time for the next dose, skip the one you missed and go back to the regular schedule. Do not give two doses at once.\r\n\r\n<p><strong>What is the most important information I should know?</strong><br>\r\nGive Proin ER exactly as your veterinarian prescribes. Missed doses could result in a recurrence of symptoms. \r\n\r\n<p>Contact your veterinarian if your pet becomes restless, irritable or the incontinence persists or gets worse.</p>\r\n\r\n\r\n<p><strong>Who should not take it?</strong><br>\r\nNot for use in animals hypersensitive (allergic) to it. Do not use in animals with glaucoma, enlarged prostate, hyperthyroidism, diabetes mellitus, heart problems, or high blood pressure.\r\n\r\n<p>Do not use in pregnant, or lactating animals (female animals nursing their young).</p>\r\n\r\n\r\n<p><strong>What side effects may be seen when taking Proin ER?</strong><br>\r\nMay see restlessness or irritability. You may also see increased heart rate, increased blood pressure, or loss of appetite. If you see any of these signs, or the incontinence persists or worsens, contact your veterinarian.\r\n\r\n<p>If your pet experiences an allergic reaction to the medication, signs may include facial swelling, hives,scratching, sudden onset of diarrhea, vomiting, shock, seizures, pale gums, cold limbs, or coma. If you observe any of these signs, contact your veterinarian immediately.\r\n</p>\r\n\r\n<p><strong>How is it stored?</strong><br>\r\nStore Proin ER at room temperature away from moisture and heat. Keep this medication away from children and pets.\r\n\r\n<p><strong>What should I do if I know of or suspect there has been an overdose?</strong><br>\r\nShould overdose occur, you may see loss of appetite, lethargy, increased blood pressure, increased heart rate, weakness, collapse, rapid respiration, pale gums, heart failure, seizures, or coma.\r\n\r\n<p>If you know or suspect your pet has had an overdose, or if you observe any of these signs in your pet, contact your veterinarian immediately.</p>\r\n\r\n\r\n<p><strong>What should I avoid when giving my pet Proin ER?</strong><br>\r\nConsult your veterinarian before using Proin ER with any other medications, including vitamins and\r\nsupplements, ephedrine, epinephrine, or beta-blockers (like propranolol), since interactions may occur.\r\n\r\n<p>Do not use with or within 2-5 weeks of using monoamine oxidase inhibitors (MAOIs) such as selegiline (deprenyl, Anipryl), isoniazid, or amitraz (an ingredient in some flea collars and in Mitaban, used to treat mange). Consult your veterinarian before using other medications or tick collars along with Proin ER.\r\n</p>\r\n<p>There is an increased risk of high blood pressure if used with non-steroidal anti-inflammatory (NSAID) drugs (e.g., aspirin, carprofen (Novox or Rimadyl), etodolac (EtoGesic), meloxicam (Metacam), firocoxib (Previcox), deracoxib (Deramaxx), tepoxalin (Zubrin) or tricyclic antidepressants (e.g., amitriptyline or clomipramine). There is also an increased risk of irregular heart rhythms if used with digoxin.\r\n</p>"
            }
        },
        {
            "id": 197618,
            "pharmainfo": null
        },
        {
            "id": 197619,
            "pharmainfo": null
        },
        {
            "id": 197620,
            "pharmainfo": null
        },
        {
            "id": 197621,
            "pharmainfo": null
        },
        {
            "id": 197622,
            "pharmainfo": null
        },
        {
            "id": 197623,
            "pharmainfo": null
        },
        {
            "id": 197624,
            "pharmainfo": null
        },
        {
            "id": 197625,
            "pharmainfo": null
        },
        {
            "id": 197626,
            "pharmainfo": null
        },
        {
            "id": 197627,
            "pharmainfo": null
        },
        {
            "id": 197628,
            "pharmainfo": null
        },
        {
            "id": 197629,
            "pharmainfo": null
        },
        {
            "id": 197630,
            "pharmainfo": null
        },
        {
            "id": 197631,
            "pharmainfo": null
        },
        {
            "id": 197632,
            "pharmainfo": null
        },
        {
            "id": 197633,
            "pharmainfo": null
        },
        {
            "id": 197634,
            "pharmainfo": null
        },
        {
            "id": 197635,
            "pharmainfo": null
        },
        {
            "id": 197636,
            "pharmainfo": null
        },
        {
            "id": 197637,
            "pharmainfo": null
        },
        {
            "id": 197638,
            "pharmainfo": null
        },
        {
            "id": 197639,
            "pharmainfo": null
        },
        {
            "id": 197640,
            "pharmainfo": null
        },
        {
            "id": 197641,
            "pharmainfo": null
        },
        {
            "id": 197642,
            "pharmainfo": null
        },
        {
            "id": 197643,
            "pharmainfo": null
        },
        {
            "id": 197644,
            "pharmainfo": null
        },
        {
            "id": 197645,
            "pharmainfo": null
        },
        {
            "id": 197646,
            "pharmainfo": null
        },
        {
            "id": 197647,
            "pharmainfo": null
        },
        {
            "id": 197648,
            "pharmainfo": null
        },
        {
            "id": 197649,
            "pharmainfo": null
        },
        {
            "id": 197650,
            "pharmainfo": null
        },
        {
            "id": 197651,
            "pharmainfo": null
        },
        {
            "id": 197652,
            "pharmainfo": null
        },
        {
            "id": 197653,
            "pharmainfo": null
        },
        {
            "id": 197654,
            "pharmainfo": null
        },
        {
            "id": 197655,
            "pharmainfo": null
        },
        {
            "id": 197656,
            "pharmainfo": null
        },
        {
            "id": 197657,
            "pharmainfo": null
        },
        {
            "id": 197658,
            "pharmainfo": null
        },
        {
            "id": 197659,
            "pharmainfo": null
        },
        {
            "id": 197660,
            "pharmainfo": null
        },
        {
            "id": 197661,
            "pharmainfo": null
        },
        {
            "id": 197662,
            "pharmainfo": null
        },
        {
            "id": 197663,
            "pharmainfo": null
        },
        {
            "id": 197664,
            "pharmainfo": null
        }
    ]
}